Evaluation of immune responses in adults after vaccination or infection

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate immune responses in adults aged 18 and older by collecting blood and tissue samples from individuals who have recently been vaccinated or recovered from infections. Participants will undergo clinical evaluations and provide various specimens, including blood and mucosal samples, to help researchers understand the immune correlates of protection. The data collected will enhance knowledge about immune responses and assist in the development of vaccines against infectious diseases. Participation is voluntary, and all procedures are optional.

Why it matters

Who can join: the full rules

* INCLUSION CRITERIA:

  1. 18 years of age or older.
  2. Able to provide proof of identity to the satisfaction of the study clinician completing the enrollment process.
  3. Able and willing to complete the informed consent process.
  4. Willing to donate specimens for storage to be used for research.

EXCLUSION CRITERIA:

1. Any medical, psychiatric, occupational condition or other condition that, in the judgment of the investigator, is a contraindication to protocol participation or impairs a participant s ability to give informed consent.
2. Bleeding disorder diagnosed by a doctor (e.g., factor deficiency, coagulopathy, or platelet disorder requiring special precautions), use of anticoagulant medications for an ongoing medical condition, significant bruising or bleeding difficulties with intramuscular injections or blood draws. \[Note: Participants taking anticoagulants, such as aspirin, prophylactically may be considered on a case to case basis.\]

Where it's running

• National Institutes of Health Clinical Center
  Bethesda, Maryland, United States Recruiting

Study contacts

• Principal investigator: Lesia K Dropulic, M.D. — National Institute of Allergy and Infectious Diseases (NIAID)
• Study coordinator: OPS Team, VRC
• Email: vrcops@nih.gov
• Phone: Not Listed

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.