Clinical trial Recruiting at 1 site Observational Ages 18 to 100

Evaluation of adults with endocrine and metabolic conditions

Official title: Evaluation of Adults With Endocrine-Related Conditions

Run by National Institutes of Health Clinical Center (CC) · NCT02830308 · Data updated 2026-11-12

This study is looking to learn more about adults with hormone and metabolism issues, like diabetes and thyroid problems, by checking their health and collecting samples for future research.

More Endocrine System Diseases trials

Quick facts

Study typeObservational
Ages18 Years to 100 Years
SexAll
Enrollment1250 (estimated)
SponsorNational Institutes of Health Clinical Center (CC)
NIH
Locations1 site (Bethesda, Maryland)
StatusRecruiting
StartedJuly 9, 2016
Main results expectedDecember 20, 2029
Study endsDecember 31, 2029
Registry record updatedSeptember 28, 2026
Trial IDNCT02830308 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 years and older with known or suspected endocrine disorders.

Probably not a fit

Patients under 18 years old or those with severe medical conditions that could complicate participation may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to gather data on adults with known or suspected endocrine or metabolic disorders, such as diabetes and thyroid disease. Participants will undergo a medical history review, physical examination, and various laboratory tests to assess their conditions. The study seeks to enhance understanding of these disorders and train healthcare providers in their diagnosis and treatment. Additionally, it will collect samples for future research, including genetic studies.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnosis and treatment options for patients with endocrine and metabolic disorders.

How similar studies have gone: Other studies focusing on endocrine disorders have shown promise in improving understanding and treatment, making this approach both relevant and potentially impactful.

Who can join: the full rules

Show full inclusion / exclusion criteria
* INCLUSION CRITERIA:
* Participants with known or suspected endocrine disorder age 18 years and older are eligible for this protocol. Protocol investigators will make the actual selection of subjects most appropriate for clinical evaluation.
* Relatives ages 18 years and older may be enrolled if clinically indicated for the diagnosis of a proband.

EXCLUSION CRITERIA:

* Anyone under the age of 18 years old
* Any medical, physical, psychiatric, or social conditions, which, in the opinion of the investigators, would make participation in this protocol not in the best interest of the subject. Subjects who are critically ill, unstable, or with severe organ failure that may affect/limit the endocrine evaluation and place unsustainable demands on Clinical Center or NIDDK resources.

Where it's running

  • National Institutes of Health Clinical Center
    Bethesda, Maryland, United States
    Recruiting

Study contacts

  • Principal investigator: Marissa F Lightbourne, M.D. — National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  • Study coordinator: Marissa F Lightbourne, M.D.
  • Email: diabetesandendocrineclinic@nih.gov
  • Phone: (301) 827-0033

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Myokines in metabolic and endocrine diseases linked to sarcopenia

    This study tests whether myokines can serve as biomarkers or drivers of sarcopenia and sarcopenic obesity in people with metabolic or endocrine diseases.

    Recruiting Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Woluwe-Saint-Pierre - Sint-Pieters-Woluwe · NCT07703683

  • Evaluation of children with endocrine and metabolic conditions

    This study is testing how endocrine and metabolic disorders affect children from 3 months to 18 years old by looking at their medical history and physical exams, and it may involve family members in genetic testing to help with diagnosis.

    Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT02769975

  • Improving diagnosis and treatment of pheochromocytoma

    This study is testing new ways to find and treat pheochromocytomas, which are tumors from the adrenal glands, to help improve care for people with this condition.

    Recruiting Phase 1 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT00004847

  • ETHY-001 safety and activity in Thyroid Eye Disease (TED)

    This study tests ETHY-001 versus placebo to see if it is safe, tolerable, and shows activity in people with thyroid eye disease.

    Recruiting at 2 sites Phase 1 Ethyreal Bio, Inc. · Orland Park, Illinois and 2 other locations · NCT07885605

  • AMX0035 in adults with Type 1 Diabetes

    This study tests whether 24 weeks of the oral medication AMX0035 help improves metabolic health in adults with Type 1 Diabetes compared with a placebo.

    Recruiting Phase 2 University of Washington · Seattle, Washington and 1 other locations · NCT07699380

  • Orforglipron for Type 2 Diabetes in Ramadan Fasters

    This study tests whether orforglipron helps people with type 2 diabetes who fast during Ramadan, to see if it improves blood sugar control safely.

    Recruiting at 33 sites Phase 3 Eli Lilly and Company · Agra and 39 other locations · NCT07613307

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.