Evaluation of a new navigation system for knee surgery

Evaluation of a New Navigation System in Computer-assisted Total Knee Arthroplasty

Not applicable Interventional GCS Ramsay Santé pour l'Enseignement et la Recherche · NCT05435690

This study is testing a new computer-assisted navigation system for knee surgery to see if it helps people with knee arthritis recover better than traditional surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment126 (estimated)
Ages18 Years and up
SexAll
SponsorGCS Ramsay Santé pour l'Enseignement et la Recherche Academic / other
Locations1 site (Lyon)
Trial IDNCT05435690 on ClinicalTrials.gov

What this trial studies

This study evaluates a new navigation system designed for computer-assisted total knee arthroplasty in patients with gonarthrosis. It is a single-blind, randomized, prospective comparative study that involves two groups: one receiving conventional arthroplasty and the other receiving the computer-assisted approach. Patients will be assessed at three different time points: before the surgery, three months post-surgery, and twelve months post-surgery to determine the effectiveness of the new navigation system. The goal is to improve surgical outcomes and patient recovery.

Who should consider this trial

Good fit: Ideal candidates are adults with primary uni or bilateral gonarthrosis who are indicated for total knee arthroplasty.

Not a fit: Patients with a history of knee fractures, previous arthroplasty, or severe preoperative conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical precision and better recovery outcomes for patients undergoing knee arthroplasty.

How similar studies have performed: Other studies have shown promising results with computer-assisted techniques in orthopedic surgery, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult man or woman who has signed the informed consent for participation in the study,
* Patient with primary uni or bilateral gonarthrosis
* For whom an indication for total knee arthroplasty has been given

Exclusion Criteria:

* History of fracture, arthroplasty or osteotomy of the knee
* Severe preoperative laxity warranting a constrained prosthesis
* Inflammatory rheumatic disease or any other progressive concomitant condition that may impact on the patient's functional prognosis
* Traumatic articular or extra-articular deformities of the lower limb
* Neurological disease, after-effects of a stroke
* Mental deficiency or any other reason that may hinder the understanding or the strict application of the protocol
* Patient not affiliated to the French social security system
* Patient under legal protection, guardianship or curatorship
* Patient already included in another therapeutic study protocol or having participated in another trial in the previous three months

Where this trial is running

Lyon

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Gonarthrosis
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.