Evaluating vascular changes in living kidney donors
Vascular Remodeling After Living Kidney Donation
This study is testing how blood vessels change in people who donate a kidney to see if these changes affect their heart health over time.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 44 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 1 site (Paris) |
| Trial ID | NCT05073913 on ClinicalTrials.gov |
What this trial studies
This study aims to assess the vascular remodeling in individuals who are candidates for living kidney donation. It focuses on the changes in small, medium, and large blood vessels before and one year after the donation, using non-invasive techniques. The study seeks to establish a connection between vascular remodeling and cardiovascular risk in kidney donors, which has not been thoroughly explored in previous research. By understanding these changes, the study hopes to refine the evaluation process for potential kidney donors.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals who are planning to donate a kidney and are affiliated with national health insurance.
Not a fit: Patients who are pregnant, breastfeeding, or have allergies to specific contrast agents or gels may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved assessment and management of cardiovascular risks in living kidney donors.
How similar studies have performed: While the specific approach of this study may be novel, there is a growing body of research indicating the importance of vascular health in kidney donors, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * candidate to living kidney donation * affiliated to national health insurance * capable of understanding the consequences of participating to the study * written informed consent Exclusion Criteria: * pregnancy * breastfeeding * allergy to iodinated contrast agents * allergy to echographic gel, allergy to cutaneous dressings * cutaneous lesions preventing the ultrasonography probe to be applied on the skin * participation to a drug trial
Where this trial is running
Paris
- Hôpital Necker — Paris, France (Recruiting)
Study contacts
- Principal investigator: Marie COURBEBAISSE, MD, PhD — marie.courbebaisse@aphp.fr
- Study coordinator: Marie COURBEBAISSE, MD, PhD
- Email: marie.courbebaisse@aphp.fr
- Phone: +33 1 56 09 39 69
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.