Evaluating treatment options for aortic valve stenosis
Official title: Future Optimal Research and Care Evaluation - Aortic Stenosis
Run by St. Antonius Hospital · NCT06168123 · Data updated 2026-11-12
This study is testing how different treatments for aortic valve stenosis, like surgery and other options, affect patients' quality of life and survival.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 110 Years |
| Sex | All |
| Enrollment | 800 (estimated) |
| Sponsor | St. Antonius Hospital Academic / other |
| Locations | 1 site (Nieuwegein) |
| Status | Recruiting |
| Started | November 27, 2023 |
| Main results expected | August 1, 2027 |
| Study ends | August 1, 2027 |
| Registry record updated | December 3, 2024 |
| Trial ID | NCT06168123 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old diagnosed with severe or moderate aortic stenosis.
✕Probably not a fit
Patients with mild aortic stenosis or those who do not meet the age criteria may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the impact of different treatment modalities for aortic valve stenosis, including surgical aortic valve replacement, transcatheter aortic valve implantation, and conservative management. It will evaluate how these treatments affect patients' quality of life and survival rates. Quality of life questionnaires will be utilized alongside standard care to gather comprehensive data on patient outcomes. The study seeks to inform optimal long-term management strategies for individuals with aortic stenosis.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the best treatment approaches for patients with aortic stenosis, potentially improving their quality of life and survival.
How similar studies have gone: Other studies have shown success in evaluating treatment modalities for aortic stenosis, indicating that this approach is supported by existing research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Older than 18 years of age * Severe or moderate aortic stenosis No exclusion criteria are applicable to this registry
Where it's running
-
St. Antonius Hospital
Nieuwegein, Netherlands Recruiting
Study contacts
- Study coordinator: Christiaan Overduin
- Email: c.overduin@antoniusziekenhuis.nl
- Phone: +31 (0)88 320 0931
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Hydra THV Transfemoral Valve Implantation in Severe Aortic Stenosis
This registry tests how safely and effectively the Hydra THV works when implanted through the femoral artery in adults with severe symptomatic aortic stenosis.
-
Noninvasive ECG Monitoring to Support Early Discharge After TAVI for Conduction Disorders
A noninvasive ECG monitoring approach is tested to see if it safely allows patients with conduction issues after TAVI to go home earlier.
-
FAPI-PET imaging to see heart tissue changes after TAVI for aortic stenosis
Using FAPI-PET scans, doctors will see if heart scarring and function improve after TAVI in people with severe aortic stenosis compared with those treated with medication alone.
-
Ataciguat to slow progression of moderate calcific aortic valve stenosis
This trial will test whether ataciguat can slow valve calcium buildup and disease progression in adults with moderate aortic valve stenosis.
-
Registry for patients with severe aortic valve stenosis undergoing TAVR with Myval valve
This study is testing how often heart rhythm problems happen and if patients need a pacemaker after getting a new heart valve through TAVR using the Myval valve.
-
Comparing heart valve prostheses for treating aortic stenosis
This study is testing how well different types of heart valve replacements work for people with severe aortic stenosis, especially those with smaller heart openings.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.