Evaluating trace elements in follicular fluid and their impact on ICSI outcomes
Evaluation of Some Trace Elements in Follicular Fluid in Intracytoplasmic Sperm Injection(ICSI) Patients
This study is testing whether certain trace elements in follicular fluid can affect the success of ICSI treatments for women who are good responders.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 154 (estimated) |
| Ages | 25 Years to 40 Years |
| Sex | Female |
| Sponsor | Assiut University Academic / other |
| Locations | 2 sites (Asyut, Egypt and 1 other locations) |
| Trial ID | NCT06719817 on ClinicalTrials.gov |
What this trial studies
This study aims to assess the concentrations of specific trace elements found in follicular fluid and their correlation with reproductive outcomes in patients undergoing Intracytoplasmic Sperm Injection (ICSI). It focuses on good responders characterized by an Anti-Müllerian Hormone (AMH) level greater than 0.8 ng/dl and an antral follicular count exceeding four. The observational approach will involve analyzing the follicular fluid samples collected during the ICSI procedure to determine the influence of these trace elements on success rates. The findings could provide insights into optimizing ICSI outcomes based on trace element levels.
Who should consider this trial
Good fit: Ideal candidates for this study are women classified as good responders according to NICE guidelines, with an AMH level greater than 0.8 ng/dl and an antral follicular count of more than four.
Not a fit: Patients who may not benefit from this study include those identified as poor responders according to ESHRE guidelines, such as those with advanced maternal age or low ovarian response.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of how trace elements affect ICSI outcomes, potentially leading to improved fertility treatments.
How similar studies have performed: While the evaluation of trace elements in reproductive outcomes is a growing area of interest, this specific approach appears to be novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria:good responders according to NICE guidelines with AMH more than 0.8ng/dl and antral follicular count more than 4 Exclusion Criteria:Poor responders according to ESHRE guidelines as advanced maternal age poor ovarian response and according to NICE guidelines AMH less than 0.8ng/dl
Where this trial is running
Asyut, Egypt and 1 other locations
- Faculty of medicine — Asyut, Egypt, Egypt (Recruiting)
- Faculty of medicine — Asyut, Egypt, Egypt (Recruiting)
Study contacts
- Study coordinator: Fatma Ahmed Waley
- Email: www.fatma.waley@gmail.com
- Phone: 01064402617
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.