Clinical trial Recruiting at 2 sites Observational Ages 25 to 40 Women only

Evaluating trace elements in follicular fluid and their impact on ICSI outcomes

Official title: Evaluation of Some Trace Elements in Follicular Fluid in Intracytoplasmic Sperm Injection(ICSI) Patients

Run by Assiut University · NCT06719817 · Data updated 2026-11-12

This study is testing whether certain trace elements in follicular fluid can affect the success of ICSI treatments for women who are good responders.

Quick facts

Study typeObservational
Ages25 Years to 40 Years
SexWomen only
Enrollment154 (estimated)
SponsorAssiut University
Academic / other
Locations2 sites (Asyut, Egypt and 1 other locations)
StatusRecruiting
StartedNovember 24, 2024
Main results expectedAugust 20, 2026
Study endsSeptember 20, 2026
Registry record updatedDecember 6, 2024
Trial IDNCT06719817 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are women classified as good responders according to NICE guidelines, with an AMH level greater than 0.8 ng/dl and an antral follicular count of more than four.

Probably not a fit

Patients who may not benefit from this study include those identified as poor responders according to ESHRE guidelines, such as those with advanced maternal age or low ovarian response.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess the concentrations of specific trace elements found in follicular fluid and their correlation with reproductive outcomes in patients undergoing Intracytoplasmic Sperm Injection (ICSI). It focuses on good responders characterized by an Anti-Müllerian Hormone (AMH) level greater than 0.8 ng/dl and an antral follicular count exceeding four. The observational approach will involve analyzing the follicular fluid samples collected during the ICSI procedure to determine the influence of these trace elements on success rates. The findings could provide insights into optimizing ICSI outcomes based on trace element levels.

Why it matters

Potential benefit: If successful, this study could enhance the understanding of how trace elements affect ICSI outcomes, potentially leading to improved fertility treatments.

How similar studies have gone: While the evaluation of trace elements in reproductive outcomes is a growing area of interest, this specific approach appears to be novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:good responders according to NICE guidelines with AMH more than 0.8ng/dl and antral follicular count more than 4 Exclusion Criteria:Poor responders according to ESHRE guidelines as advanced maternal age poor ovarian response and according to NICE guidelines AMH less than 0.8ng/dl

Where it's running

  • Faculty of medicine
    Asyut, Egypt, Egypt
    Recruiting
  • Faculty of medicine
    Asyut, Egypt, Egypt
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.