Evaluating three suturing techniques for closing cesarean incisions

Niche Investigated: Closure of Hysterotomy & Evaluation of 3 Suturing Techniques (Running, Interrupted, and Locked)

Not applicable Interventional Cairo University · NCT06695793

This study is testing which of three different stitching methods for closing cesarean incisions helps women heal better and have fewer issues with their scars after surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment225 (estimated)
Ages18 Years to 35 Years
SexFemale
SponsorCairo University Academic / other
Locations5 sites (Cairo and 4 other locations)
Trial IDNCT06695793 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of three different suturing techniques—Running, Interrupted, and Locked—on the formation of a cesarean scar niche in women undergoing elective cesarean sections. The participants will be women with singleton pregnancies, aged 18 to 35, and with a BMI under 30, scheduled for cesarean delivery at 38 to 40 weeks of gestation. The study aims to determine which suturing method may lead to better outcomes in terms of scar formation and healing. Participants will be monitored for their willingness to provide informed consent and meet specific health criteria.

Who should consider this trial

Good fit: Ideal candidates are women aged 18 to 35 with a singleton pregnancy scheduled for elective cesarean section.

Not a fit: Patients with known uterine anomalies, pre-existing medical conditions, or those requiring extensive suturing may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical techniques that minimize complications related to cesarean scars.

How similar studies have performed: While the specific suturing techniques have been explored in various contexts, this study's focus on their impact on cesarean scar niche formation is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Women with a singleton pregnancy scheduled for elective cesarean section
2. Gestational age at the time of cesarean section between 38 and 40 weeks.
3. Willingness to participate in the study and provide informed consent
4. Age between 18 and 35 years old.
5. BMI \<30

Exclusion Criteria:

1. Known uterine anomalies or previous uterine surgery (e.g, myomectomy, uterine septum resection)
2. Pre-existing medical conditions contraindicating cesarean delivery or affecting uterine healing (e.g., Anemia, Diabetes)
3. Current smokers.
4. Non-cephalic presentation of the fetus.
5. Low-lying anterior wall placenta and placenta previa.
6. Inability to provide informed consent (e.g., cognitive impairment, language barrier)
7. Any condition deemed by the attending physician to pose a risk to the participant or compromise the study's integrity, for example, Patients who will require excessive suturing for further hemostasis or those who require ligation of one or both uterine arteries

Where this trial is running

Cairo and 4 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Caesarean Scar Niche
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.