Clinical trial Recruiting at 1 site Observational Ages 19 to 99

Evaluating the weaning process from mechanical ventilation in medical patients

Official title: Prospective, Single-center, Observational Study on the Assessment of Process and Outcome of Protocol-based Weaning From Mechanical Ventilation in the Medical Patients

Run by Samsung Medical Center · NCT05134467 · Data updated 2026-11-12

This study looks at how to safely help adults in the ICU stop using mechanical ventilation by checking their breathing and health to see what works best.

Quick facts

Study typeObservational
Ages19 Years to 99 Years
SexAll
Enrollment1000 (estimated)
SponsorSamsung Medical Center
Academic / other
Locations1 site (Seoul)
StatusRecruiting
StartedNovember 1, 2017
Main results expectedSeptember 30, 2029
Study endsSeptember 30, 2029
Registry record updatedNovember 26, 2021
Trial IDNCT05134467 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adult patients aged 19 years and older who have been on mechanical ventilation for at least two calendar days.

Probably not a fit

Patients who are not receiving mechanical ventilation or those who have been on it for less than two days will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to describe the characteristics and factors influencing the weaning process from mechanical ventilation in adult patients in a medical intensive care unit. It involves daily assessments by respiratory care practitioners to determine patients' readiness for weaning based on their clinical stability and pulmonary function. Data on the weaning process, spontaneous breathing trials, and patient outcomes will be collected to better understand the duration and effectiveness of weaning. The study has been ongoing since November 2017 and includes all eligible patients receiving mechanical ventilation for at least two days.

Why it matters

Potential benefit: If successful, this study could improve the weaning process from mechanical ventilation, leading to better patient outcomes and reduced duration of mechanical support.

How similar studies have gone: Other studies have shown success in optimizing weaning protocols, indicating that this approach is supported by existing evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All consecutive adult patients receiving mechanical ventilation for at least two calendar days in medical intensive care units

Exclusion Criteria:

* None

Where it's running

  • Samsung Medical Center
    Seoul, South Korea
    Recruiting

Study contacts

  • Principal investigator: Kyeongman Jeon — Samsung Medical Center
  • Study coordinator: Kyeongman Jeon
  • Email: kjeon@skku.edu
  • Phone: 82-2-3410-2423

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.