Evaluating the weaning process from mechanical ventilation in medical patients

Prospective, Single-center, Observational Study on the Assessment of Process and Outcome of Protocol-based Weaning From Mechanical Ventilation in the Medical Patients

Observational Samsung Medical Center · NCT05134467

This study looks at how to safely help adults in the ICU stop using mechanical ventilation by checking their breathing and health to see what works best.

Quick facts

Study typeObservational
Enrollment1000 (estimated)
Ages19 Years to 99 Years
SexAll
SponsorSamsung Medical Center Academic / other
Locations1 site (Seoul)
Trial IDNCT05134467 on ClinicalTrials.gov

What this trial studies

This observational study aims to describe the characteristics and factors influencing the weaning process from mechanical ventilation in adult patients in a medical intensive care unit. It involves daily assessments by respiratory care practitioners to determine patients' readiness for weaning based on their clinical stability and pulmonary function. Data on the weaning process, spontaneous breathing trials, and patient outcomes will be collected to better understand the duration and effectiveness of weaning. The study has been ongoing since November 2017 and includes all eligible patients receiving mechanical ventilation for at least two days.

Who should consider this trial

Good fit: Ideal candidates for this study are adult patients aged 19 years and older who have been on mechanical ventilation for at least two calendar days.

Not a fit: Patients who are not receiving mechanical ventilation or those who have been on it for less than two days will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the weaning process from mechanical ventilation, leading to better patient outcomes and reduced duration of mechanical support.

How similar studies have performed: Other studies have shown success in optimizing weaning protocols, indicating that this approach is supported by existing evidence.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All consecutive adult patients receiving mechanical ventilation for at least two calendar days in medical intensive care units

Exclusion Criteria:

* None

Where this trial is running

Seoul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Ventilator Lung
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.