Evaluating the weaning process from mechanical ventilation in medical patients
Official title: Prospective, Single-center, Observational Study on the Assessment of Process and Outcome of Protocol-based Weaning From Mechanical Ventilation in the Medical Patients
Run by Samsung Medical Center · NCT05134467 · Data updated 2026-11-12
This study looks at how to safely help adults in the ICU stop using mechanical ventilation by checking their breathing and health to see what works best.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 19 Years to 99 Years |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Samsung Medical Center Academic / other |
| Locations | 1 site (Seoul) |
| Status | Recruiting |
| Started | November 1, 2017 |
| Main results expected | September 30, 2029 |
| Study ends | September 30, 2029 |
| Registry record updated | November 26, 2021 |
| Trial ID | NCT05134467 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adult patients aged 19 years and older who have been on mechanical ventilation for at least two calendar days.
✕Probably not a fit
Patients who are not receiving mechanical ventilation or those who have been on it for less than two days will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to describe the characteristics and factors influencing the weaning process from mechanical ventilation in adult patients in a medical intensive care unit. It involves daily assessments by respiratory care practitioners to determine patients' readiness for weaning based on their clinical stability and pulmonary function. Data on the weaning process, spontaneous breathing trials, and patient outcomes will be collected to better understand the duration and effectiveness of weaning. The study has been ongoing since November 2017 and includes all eligible patients receiving mechanical ventilation for at least two days.
Why it matters
Potential benefit: If successful, this study could improve the weaning process from mechanical ventilation, leading to better patient outcomes and reduced duration of mechanical support.
How similar studies have gone: Other studies have shown success in optimizing weaning protocols, indicating that this approach is supported by existing evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All consecutive adult patients receiving mechanical ventilation for at least two calendar days in medical intensive care units Exclusion Criteria: * None
Where it's running
-
Samsung Medical Center
Seoul, South Korea Recruiting
Study contacts
- Principal investigator: Kyeongman Jeon — Samsung Medical Center
- Study coordinator: Kyeongman Jeon
- Email: kjeon@skku.edu
- Phone: 82-2-3410-2423
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.