Evaluating the use of nasogastric tubes in treating small bowel obstruction due to adhesions

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of nasogastric tube (NGT) insertion in patients with uncomplicated acute adhesive small bowel obstruction (ASBO). The study compares non-operative management with and without NGT to determine the best approach for alleviating symptoms and improving patient outcomes. Participants will be monitored for 72 hours, and the trial aims to provide insights into the management of ASBO, which is a significant public health concern. The study is conducted at multiple hospitals in France, focusing on patients who meet specific eligibility criteria.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Presence of an obstruction believed to be secondary to adhesions (abdominal pain and distention, nausea and/or vomiting, no gas and/or stool).
* Uncomplicated presentation (no signs of strangulation or peritonitis).
* IV CT scan of the abdomen consistent with an uncomplicated ASBO, (performed with a pillow to raise slightly the patient.
* Aged 18 or older.
* Provision of written, informed consent.
* Patient covered by French national health insurance.

Exclusion Criteria:

* An incarcerated and/or strangulated incisional hernia, colonic obstruction.
* No previous abdominal operation.
* Obstruction within 4 weeks after a recent operation.
* Gastrointestinal neoplasm in progress.
* Inflammatory bowel disease in progress.
* Abdominal radiotherapy in the last 6 months.
* Contraindication to intravenous contrast enhancement for the CT scan, pre-existing risks factors for pneumonitis.
* Antecedent of aspiration pneumonia.
* Age \> 85 years.
* Orientation disturbance.
* Bedridden.
* Chronic cerebrovascular disease (cerebral infarction sequelae, Parkinson disease etc).
* Dementia.
* Gastroesophageal disorder (gastroesophageal reflux)
* Pregnancy or breastfeeding.
* Patient deprived of liberty by administrative or judicial decision or placed under judicial protection (guardianship or supervision).
* Patients unable to provide informed consent.
* Age \<18 years.

Where it's running

• Amiens Universitary Hospital
  Amiens, France Recruiting

Study contacts

• Study coordinator: Jean Marc Regimbeau, Pr
• Email: regimbeau.jean-marc@chu-amiens.fr
• Phone: 322 088 897

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.