Clinical trial Recruiting at 2 sites Observational Ages 18 and up

Evaluating the Use of Advance Directives in Intensive Care

Official title: Advance Directive Implementation and Scientific Evaluation (ADVISE) Study

Run by University Hospital, Basel, Switzerland · NCT04348318 · Data updated 2026-11-12

This study looks at how having advance directives affects the health outcomes of adults in the intensive care unit at University Hospital Basel.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment2000 (estimated)
SponsorUniversity Hospital, Basel, Switzerland
Academic / other
Locations2 sites (Aarau and 1 other locations)
StatusRecruiting
StartedAugust 3, 2021
Main results expectedDecember 2050
Study endsDecember 2050
Registry record updatedJune 17, 2026
Trial IDNCT04348318 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adult patients who were treated in the intensive care unit for more than 48 hours at the University Hospital Basel during the specified time frame.

Probably not a fit

Patients who have documented refusal of general consent or were treated in the intensive care unit for less than 48 hours will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to analyze the implementation and impact of advance directives on patient outcomes in the intensive care unit at the University Hospital Basel. By retrospectively extracting data from digital medical records of adult patients admitted between 2011 and 2023, the study will assess the proportion of patients with advance directives and compare their in-hospital outcomes, such as survival and neurological recovery, to those without such directives. Descriptive analyses will be utilized to provide insights into the effectiveness of advance directives in guiding treatment decisions during critical illness.

Why it matters

Potential benefit: If successful, this study could enhance the understanding of advance directives, potentially leading to improved patient outcomes and more personalized care in critical situations.

How similar studies have gone: While the specific approach of this study may be novel, previous studies have indicated that advance directives can play a significant role in patient care decisions, suggesting potential for meaningful insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* adult patients treated for more than 48 hours in the intensive care unit (post-operative or internal medicine) of the University Hospital Basel in the years 2011-2023

Exclusion Criteria:

* Patients with documented refusal of the general consent.
* Patients who have been treated in the intensive care unit for less than 48 hours

Where it's running

  • Kantonsspital Aarau
    Aarau, Switzerland
    Recruiting
  • Clinic for Intensive Care Medicine, University Hospital Basel
    Basel, Switzerland
    Recruiting

Study contacts

  • Principal investigator: Raoul Sutter, PD Dr. med — Clinic for Intensive Care Medicine, University Hospital Basel
  • Study coordinator: Raoul Sutter, PD Dr. med
  • Email: raoul.sutter@usb.ch
  • Phone: +41 61 87928

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.