Evaluating the TRiP(cast) Score for Lower Limb Trauma Patients
Inter-observer Reliability of the Assessment of the Risk of Developing a Venous Thromboembolic Event, the TRiP(Cast) Score, in Patients With Trauma to a Lower Limb Requiring Immobilisation
This study is testing a new scoring system to see if it can better identify patients with lower limb injuries who are at risk for blood clots compared to doctors' usual judgments.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 302 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Angers Government |
| Locations | 1 site (Angers) |
| Trial ID | NCT06416280 on ClinicalTrials.gov |
What this trial studies
This study aims to assess the reliability of the TRiP(cast) score in evaluating the risk of venous thromboembolism in patients with lower limb trauma requiring immobilization. It compares the TRiP(cast) score's effectiveness against clinicians' assessments using their implicit probability. The study focuses on patients presenting to emergency departments with isolated lower limb trauma and aims to identify those at high risk for thromboembolic events. By refining risk assessment, the study seeks to optimize thromboprophylaxis strategies for these patients.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old with isolated lower limb trauma requiring immobilization for at least 7 days.
Not a fit: Patients currently on anticoagulant treatment or those with trauma requiring hospitalization for more than 48 hours may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate risk assessments and tailored anticoagulation treatments for patients with lower limb trauma.
How similar studies have performed: Previous studies using the TRiP(cast) score have shown promising results in reducing unnecessary anticoagulation prescriptions without increasing thromboembolic events.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Consultation in one of the emergency departments participating in the study, * Isolated trauma to a lower limb, * Rigid immobilisation (plaster or resin) or semi-rigid immobilisation for an expected duration of at least 7 days, * Patient over 18 years of age, * Patient affiliated to or benefiting from a social security scheme, * Patients who have signed a prior informed consent form Exclusion Criteria: * Patient taking anticoagulant treatment at the time of the trauma, * Trauma requiring hospitalisation for more than 48 hours, * Pregnant, breast-feeding or parturient patients, * Patient deprived of liberty by judicial or administrative decision, * Patient under compulsory psychiatric care, * Patient under legal protection, * Patients unable to give their free and informed consent
Where this trial is running
Angers
- DOUILLET Delphine — Angers, France (Recruiting)
Study contacts
- Principal investigator: Delphine DOUILLET — University Hospital, Angers
- Study coordinator: Delphine DOUILLET
- Email: Delphine.Douillet@chu-angers.fr
- Phone: (0)241353637
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.