Evaluating the safety of Terahertz scanning on corneas

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the safety of the Terahertz (THz) scanning system in individuals with non-seeing eyes but healthy corneas. Participants will undergo THz scanning, followed by comprehensive eye examinations at various intervals to monitor visual acuity, corneal health, and nerve status. The study hypothesizes that the THz scanning system is safe for application on the human cornea, which is crucial for understanding corneal hydration and preventing conditions like corneal opacification. The findings could provide insights into non-invasive monitoring techniques for corneal diseases.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Be at least 21 years of age
* Regardless of gender (Male/Female)
* Regardless of race (Chinese/Malay/Indian/Eurasian/Others)
* Willingness and ability to follow all instructions and comply with study schedule for study visit
* Have at least 1 eye (Study eye) that is deemed functionally blind but contain healthy corneas
* Ability to hold face sufficiently stable to undergo necessary scans
* Best Spectacle Corrected Visual Acuity (BSCVA) in the study eye of hand motion or worse

Exclusion Criteria:

* Pregnant/Breast-feeding women
* Eyes with previous major surgery on the cornea such as corneal transplantation, refractive surgery, corneal cross-linking procedure
* Eyes with previous infectious keratitis
* Eyes with long-term use of glaucoma eye drops
* Eyes with known moderate or server meibomian gland dysfunction
* Eyes with active inflammation or infection, or chronic ocular surface inflammation
* Systemic diseases that affect the ocular surface, such as systemic autoimmune diseases

Where it's running

• Singapore National Eye Centre
  Singapore, Singapore, Singapore Recruiting

Study contacts

• Study coordinator: Yu-Chi Liu
• Email: liu.yu.chi@snec.com.sg
• Phone: 65 65767287

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.