Evaluating the safety of ENC-201-CED for Type 1 diabetes

A Safety and Tolerability Study of ENC=201-CED in Participants With Type 1 Diabetes Receiving Islet Infusion

Phase 1 Interventional Encellin · NCT06408311

This study is testing a new treatment called ENC-201-CED to see if it's safe for people with Type 1 diabetes when given under the skin.

Quick facts

PhasePhase 1
Study typeInterventional
Enrollment10 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorEncellin Industry-sponsored
Locations2 sites (Toronto, Ontario and 1 other locations)
Trial IDNCT06408311 on ClinicalTrials.gov

What this trial studies

This study aims to assess the safety and tolerability of ENC-201-CED when administered in the subcutaneous space of patients with Type 1 diabetes. It involves a Phase 1 interventional approach, focusing on candidates who meet the eligibility criteria for standard of care islet infusion. The study will monitor participants for any adverse effects and overall response to the treatment.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals with Type 1 diabetes who qualify for standard of care islet infusion.

Not a fit: Patients who do not meet the eligibility criteria for standard of care islet infusion may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could improve glucose metabolism and overall management of Type 1 diabetes.

How similar studies have performed: There have been other studies exploring similar interventions, but the specific approach of ENC-201-CED is novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Candidates must satisfy site's eligibility for standard of care islet infusion.

Exclusion Criteria:

* Candidates are excluded based on the site's criteria for standard of care islet infusion.

Where this trial is running

Toronto, Ontario and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Diabetes Mellitus, Type 1Diabetes MellitusGlucose MetabolismIslet InfusionPancreas Transplant
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.