Evaluating the role of PET-CT in managing invasive fungal infections

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This national multicenter prospective cohort study aims to assess the added value of 18F-FDG PET-CT in the management of invasive fungal infections (IFI). It will compare the effectiveness of PET-CT against conventional radiological studies in terms of disease characterization, staging, and monitoring treatment response. Participants will undergo a PET-CT scan as part of their diagnostic work-up, and researchers will analyze how this imaging technique influences patient management and prognostic evaluations. The study will include patients with fungemia and focal IFIs, following established diagnostic criteria.

Why it matters

Who can join: the full rules

Inclusion criteria:

* 18-year-old adult patients
* who are admitted with a diagnosis of invasive fungal infection
* who able to undergo a one 18F-FDG PET-CT
* who give their informed consent.

Exclusion criteria:

* concomitant active bacterial infection likely to produce uptake in organs and tissues
* recent surgery in the area of the IFI (in the previous 3 months)
* other medical conditions that interfere with the development of the study ( e.g., inability to tolerate the performance of the test during the required time, pregnancy)
* terminal situation.

Where it's running

• Hospital Universitario Puerta de Hierro
  Majadahonda, Madriid, Spain Recruiting
• Hospital de Bellvitge
  Barcelona, Spain Recruiting
• Hospital Universitario Clinic
  Barcelona, Spain Recruiting
• Hospital Universitario Virgen de las Nieves
  Granada, Spain Recruiting
• Hospital Infanta Leonor Hospital
  Madrid, Spain Recruiting
• Hospital Universitario Gregorio Marañón
  Madrid, Spain Recruiting

Study contacts

• Principal investigator: Ana Fernández Cruz, MDPhD — Hospital Puerta de Hierro-Majadahonda
• Study coordinator: Andrea Gutiérrez Villanueva, MD
• Email: a.gutierrezv@hotmail.com
• Phone: +34618157518

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.