Evaluating the properties of the thoracic aorta in patients with ascending aortic aneurysm
Official title: Prospective Evaluation of the Biomechanical Properties of the Thoracic Aorta Coupling Magnetic Resonance Imaging and In-vitro Elasticity Tests in Patients With Ascending Aortic Aneurysm
Run by Centre Hospitalier Universitaire Dijon · NCT03746964 · Data updated 2026-11-12
This study is testing how the thoracic aorta behaves in patients with an ascending aortic aneurysm who are about to have surgery, to see if it can help improve treatment and monitoring.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Centre Hospitalier Universitaire Dijon Academic / other |
| Locations | 1 site (Dijon) |
| Status | Recruiting |
| Started | December 17, 2018 |
| Main results expected | December 2026 |
| Study ends | February 2027 |
| Registry record updated | January 9, 2026 |
| Trial ID | NCT03746964 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old who have been diagnosed with an ascending aortic aneurysm and are scheduled for surgical replacement.
✕Probably not a fit
Patients who are not eligible due to MRI contraindications or those undergoing emergency surgical procedures may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to assess the biomechanical properties of the thoracic aorta in patients diagnosed with ascending aortic aneurysm who are scheduled for surgical replacement. By coupling magnetic resonance imaging (MRI) with in-vitro elasticity tests, the research seeks to enhance the understanding of aortic behavior, which could lead to improved surgical indications and monitoring techniques. The observational nature of the study allows for the collection of data without altering the standard treatment protocols for participants.
Why it matters
Potential benefit: If successful, this study could lead to better surgical outcomes and monitoring strategies for patients with ascending aortic aneurysms.
How similar studies have gone: While the biomechanical properties of the aorta are not extensively studied, similar approaches using MRI and elasticity testing have shown promise in related cardiovascular research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Person who has given oral consent * Patient with ascending aortic aneurysm with surgical indication for replacement * Age \> 18 years old * Scheduled surgery Exclusion Criteria: * Person not affiliated to the national health insurance system * Protected adult * Pregnant or breastfeeding woman * MRI Contraindication * Emergency surgical procedure
Where it's running
-
Chu Dijon Bourogne
Dijon, France Recruiting
Study contacts
- Study coordinator: Comlan BLITTI
- Email: comlanmawuko.blitti@chu-dijon.fr
- Phone: +33 3 80 29 33 52
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.