Evaluating the properties of the thoracic aorta in patients with ascending aortic aneurysm
Prospective Evaluation of the Biomechanical Properties of the Thoracic Aorta Coupling Magnetic Resonance Imaging and In-vitro Elasticity Tests in Patients With Ascending Aortic Aneurysm
This study is testing how the thoracic aorta behaves in patients with an ascending aortic aneurysm who are about to have surgery, to see if it can help improve treatment and monitoring.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire Dijon Academic / other |
| Locations | 1 site (Dijon) |
| Trial ID | NCT03746964 on ClinicalTrials.gov |
What this trial studies
This study aims to assess the biomechanical properties of the thoracic aorta in patients diagnosed with ascending aortic aneurysm who are scheduled for surgical replacement. By coupling magnetic resonance imaging (MRI) with in-vitro elasticity tests, the research seeks to enhance the understanding of aortic behavior, which could lead to improved surgical indications and monitoring techniques. The observational nature of the study allows for the collection of data without altering the standard treatment protocols for participants.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old who have been diagnosed with an ascending aortic aneurysm and are scheduled for surgical replacement.
Not a fit: Patients who are not eligible due to MRI contraindications or those undergoing emergency surgical procedures may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better surgical outcomes and monitoring strategies for patients with ascending aortic aneurysms.
How similar studies have performed: While the biomechanical properties of the aorta are not extensively studied, similar approaches using MRI and elasticity testing have shown promise in related cardiovascular research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Person who has given oral consent * Patient with ascending aortic aneurysm with surgical indication for replacement * Age \> 18 years old * Scheduled surgery Exclusion Criteria: * Person not affiliated to the national health insurance system * Protected adult * Pregnant or breastfeeding woman * MRI Contraindication * Emergency surgical procedure
Where this trial is running
Dijon
- Chu Dijon Bourogne — Dijon, France (Recruiting)
Study contacts
- Study coordinator: Comlan BLITTI
- Email: comlanmawuko.blitti@chu-dijon.fr
- Phone: +33 3 80 29 33 52
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.