Evaluating the Prognostic Value of Hemodynamic Indices in Coronary Artery Disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the prognostic value of lesion-specific hemodynamic indices, such as ΔFFR and RFR, in patients with coronary artery disease. It aims to assess how these indices, alongside traditional measures like % diameter stenosis and FFR, can improve risk prediction for patients undergoing percutaneous coronary intervention (PCI). The study will also explore the implications of post-PCI FFR in conjunction with various clinical and disease characteristics to develop a comprehensive risk prediction model. By doing so, it seeks to enhance the understanding of local hemodynamics in predicting patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age ≥20 years
2. All comers who underwent successful FFR measurement and pullback tracing

Exclusion Criteria:

1. Chronic renal failure (estimated glomerular filtration rate \<30)
2. ST-elevation myocardial infarction within 72 hours or previous coronary artery bypass graft surgery history
3. Primary myocardial or valvular disease
4. Left ventricular ejection fraction \< 30%
5. Hemodynamically unstable clinical conditions
6. Life expectancy \< 2 years

Where it's running

• Seoul National University Hospital
  Seoul, South Korea Recruiting

Study contacts

• Principal investigator: Bon-Kwon Koo, MD, PhD — Seoul National University Hospital
• Study coordinator: Bon-Kwon Koo, MD, PhD
• Email: bkkoo@snu.ac.kr
• Phone: +82-2-2072-2062

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.