Evaluating the need for repeat ERCP after treating biliary leaks

Validation of a Clinical Prediction Rule to Determine the Need for Repeat ERCP After Endoscopic Treatment of Postsurgical Biliary Leaks

University of Calgary · NCT05141942

This study is trying to see if patients who have had a procedure for biliary leaks really need to have another procedure to remove stents and check for leaks again.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Calgary (other)
Drugs / interventionsradiation
Locations1 site (Calgary, Alberta)
Trial IDNCT05141942 on ClinicalTrials.gov

What this trial studies

This observational study focuses on patients who have undergone endoscopic retrograde cholangiopancreatography (ERCP) for suspected post-surgical biliary leaks. It aims to assess the necessity of performing a repeat ERCP for stent removal and cholangiogram, following standard procedures. Data will be collected prospectively by a research assistant, including patient demographics and pre-procedural information. The study seeks to clarify the best practices for managing biliary leaks and the implications of repeat ERCP procedures.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older who are undergoing ERCP for suspected post-surgical biliary leaks.

Not a fit: Patients who have non-surgical biliary leaks or those who have previously undergone unsuccessful ERCP will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved management strategies for biliary leaks, potentially reducing patient exposure to unnecessary procedures.

How similar studies have performed: While there is limited data on the necessity of repeat ERCP in this specific context, similar studies have explored ERCP effectiveness in managing biliary leaks, indicating a need for further investigation.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients having ERCP for suspected post-surgical biliary leak;
* age 18 years or older
* able to give informed consent to involvement.

Exclusion Criteria:

* Unable or unwilling to provide informed consent;
* age \< 18 years;
* non-surgical biliary leak;
* previous ERCP with sphincterotomy;
* previous treatment or attempted treatment of biliary leak;
* unsuccessful initial ERCP.

Where this trial is running

Calgary, Alberta

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Bile Leak

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.