Evaluating the need for antibiotics after salivary duct stent placement

Determining the Necessity for Postoperative Antibiotics After Salivary Stent Placement

PHASE4 · Our Lady of the Lake Hospital · NCT03333408

This study is testing if patients who have a salivary duct stent placed really need antibiotics after surgery to prevent infections.

Quick facts

PhasePHASE4
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years and up
SexAll
SponsorOur Lady of the Lake Hospital (other)
Locations1 site (Baton Rouge, Louisiana)
Trial IDNCT03333408 on ClinicalTrials.gov

What this trial studies

This study investigates whether postoperative antibiotics are necessary for patients who have undergone salivary duct stent placement. It involves adult patients who will be randomly assigned to receive either postoperative antibiotics or no antibiotics following their surgery. The aim is to assess the potential risks associated with antibiotic use, such as gastrointestinal disturbances and antibiotic resistance, against the benefits of preventing infections. The study is conducted at Our Lady of the Lake Regional Medical Center in Baton Rouge, Louisiana.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older undergoing salivary duct surgery and stent placement.

Not a fit: Patients with acute infections, immunocompromised conditions, or those unwilling to participate in the randomized assignment may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could reduce unnecessary antibiotic use and its associated side effects in patients undergoing salivary duct procedures.

How similar studies have performed: Other studies have shown mixed results regarding the necessity of postoperative antibiotics in surgical scenarios, indicating that this investigation is relevant and timely.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All adult patients (18 years of age or older) who are undergoing salivary duct surgery and stent placement at Our Lady of the Lake Regional Medical Center

Exclusion Criteria:

* Patients who are unwilling to consent to the study and/or to being placed in a randomized arm of either receiving post-operative antibiotics or not receiving post-operative antibiotics
* Patients with acute infections at the time of surgery
* Patients who are immunocompromised
* Patients who are recruited but then have early dislodgement of the stent
* Patients who do not complete their postoperative antibiotic therapy due to intolerance or antibiotic side effects. However, data on these patients will be recorded to provide an observational results that will support the need for this investigation on antibiotic use.
* Patients who are in the non-post operative antibiotic arm but choose to put themselves on antibiotics without consultation from the physician

Where this trial is running

Baton Rouge, Louisiana

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Salivary Duct

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.