Evaluating the impact of zolpidem on recovery after lumbar spine fusion surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess whether administering zolpidem, a sleep aid, around the time of lumbar spine fusion surgery can enhance patient-reported outcomes. Patients aged 18 to 75 with degenerative lumbar disease will be randomly assigned to receive either zolpidem or a placebo starting two days before surgery and continuing for five days post-surgery. The focus is on one- to three-level spinal fusion procedures, and the outcomes will be measured based on patient feedback regarding their recovery and pain levels.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* degenerative lumbar disease
* age of 18-75
* undergoing open primary one- to three-level lumbar fusion

Exclusion Criteria:

* currently use a sleep aid nightly
* diagnosed with insomnia or sleep apnea
* history of delirium with opiates or zolpidem
* allergic to opiates or zolpidem
* had previous lumbar spine surgery
* undergoing minimally invasive lumbar fusion,
* undergoing lumbar fusion for fracture, infection, tumor, or an inflammatory spondyloarthropathy

Where it's running

• Keck Medical Center of USC
  Los Angeles, California, United States Recruiting

Study contacts

• Study coordinator: Pui Yan, MS
• Email: puiyan@med.usc.edu
• Phone: 323-442-6984

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.