Evaluating the impact of perinephric fat thickness on kidney function after donation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate whether perirenal fat thickness (PRAT) serves as a marker for visceral obesity and its effects on kidney function and blood pressure in living kidney donors. Participants will include individuals scheduled for nephrectomy, with specific BMI and PRAT thickness criteria. The study will assess PRAT morphology and inflammation, correlating these factors with renal outcomes and hypertension over a period of 4-6 months post-donation. Data will be collected through medical records and various health assessments during a screening visit.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Participants in this study will be restricted to living kidney transplant donors (LKDs). .

Exclusion Criteria:

* Those who do not meet Mayo Clinic Rochester's clinical criterion for donor nephrectomy.
* \>10% weight change between the donor evaluation and donor nephrectomy
* Individuals who are pregnant or are planning to become pregnant
* Inability to comply with study procedures or any condition that, in the opinion of the investigator, could increase the patient's risk by participating in the study or confound the outcome of the study.

Where it's running

• Mayo Clinic
  Rochester, Minnesota, United States Recruiting

Study contacts

• Principal investigator: Aleksandra Kukla, MD — Mayo Clinic
• Study coordinator: Jackie Reiter
• Email: reiter.jacqulyn@mayo.edu
• Phone: 507-538-2224

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.