Evaluating the impact of micro-osteoperforation on tooth movement in molar distalization

Evaluation of the Effect of Micro-osteoperforation on the Rate of Bone Anchored Molar Distalization: a Split-mouth Randomized Controlled Clinical Trial

Not applicable Interventional Cairo University · NCT06497244

This study is testing if a new technique called micro-osteoperforation can help move back the first molars faster in people getting orthodontic treatment.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment18 (estimated)
Ages16 Years and up
SexAll
SponsorCairo University Academic / other
Locations1 site (Cairo)
Trial IDNCT06497244 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to assess the effect of micro-osteoperforations (MOPs) on the rate of tooth movement during the distalization of the first molars. Participants will undergo a preparatory phase involving the placement of mini-screws and imaging, followed by an experimental phase where MOPs will be applied to one side of the maxillary molars. The study will utilize a randomized controlled design with follow-up visits to monitor progress and stability. The outcomes will be measured using digital models and cone beam computed tomography imaging.

Who should consider this trial

Good fit: Ideal candidates for this study are adults with a skeletal Class I or mild Class II relationship and full permanent dentition.

Not a fit: Patients with systemic diseases, severe skeletal Class II relationships, or dental anomalies may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance the efficiency of molar distalization, leading to shorter treatment times for patients.

How similar studies have performed: Previous studies have shown promising results with micro-osteoperforation techniques, suggesting potential effectiveness in enhancing tooth movement.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Adult patients
2. Skeletal Class I or mild Class II relationship
3. Dental class II bilaterally (non-extraction cases)
4. Full permanent dentition including 2nd maxillary molars
5. Good oral hygiene
6. Medically free

Exclusion Criteria:

1. Systemic diseases that may interfere with the treatment
2. Use of any medications that might have affected the biology of tooth movement
3. unilateral Class II molar relationship
4. extreme skeletal Class II relationship (ANB \>7°)
5. periodontal disease or alveolar bone loss
6. Patients with dental anomalies in maxillary 1st molar

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Microosteoperforations
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.