Evaluating the impact of influenza vaccination and certain medications on COVID-19 outcomes

Evaluation of Influenza Vaccination and Treatment With ACEI and ARB in the Evolution of SARS-CoV2 Infection

Consorci Sanitari de Terrassa · NCT04367883

This study is trying to see if getting the flu vaccine or taking certain medications helps people in the hospital recover better from COVID-19.

Quick facts

Study typeObservational
Enrollment3000 (estimated)
SexAll
SponsorConsorci Sanitari de Terrassa (other)
Locations1 site (Terrassa, Barcelona)
Trial IDNCT04367883 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess whether patients admitted to the Hospital de Terrassa who have received the influenza vaccine or are on treatments such as ACE inhibitors, ARBs, antihistamines, or amantadine show improved outcomes in their COVID-19 infection. The study will analyze hospital admissions, treatment histories, lengths of stay, ICU needs, and survival rates. By comparing these factors, the researchers hope to determine if these interventions can enhance patient recovery from COVID-19.

Who should consider this trial

Good fit: Ideal candidates for this study are patients admitted to the Hospital de Terrassa since March 1, 2020, regardless of the cause of admission.

Not a fit: Patients who have not been admitted to the Hospital de Terrassa or those from outside the reference area may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment protocols for COVID-19, potentially saving lives and reducing hospitalizations.

How similar studies have performed: While some studies have suggested potential benefits of influenza vaccination and certain medications in COVID-19 outcomes, this specific approach remains novel and untested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Hospital Admissions at the Hospital of Terrassa from March 1, 2020 for any cause.

Exclusion Criteria:

* None.
* For comparison of percentage of Influenza vaccination, ACEI and ARB vs general population, patients from outside the reference area of the Terrassa Health Consortium would be excluded.

Where this trial is running

Terrassa, Barcelona

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: COVID19, Influenza Vaccination, ACE Inhibitors, ARB, Antihistamine Allergy, Amantadine

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.