Evaluating the HeartLight System for treating atrial fibrillation

Post-Approval Study of the HeartLight Endoscopic Ablation System for the Treatment of Atrial Fibrillation

Not applicable Interventional CardioFocus · NCT03168659

This study is testing if the HeartLight System can safely and effectively treat people with tough-to-manage atrial fibrillation and help them feel better over time.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment250 (estimated)
Ages18 Years and up
SexAll
SponsorCardioFocus Industry-sponsored
Locations4 sites (Tucson, Arizona and 3 other locations)
Trial IDNCT03168659 on ClinicalTrials.gov

What this trial studies

This post-approval study aims to assess the clinical outcomes of patients treated with the HeartLight System for drug refractory, symptomatic, paroxysmal atrial fibrillation. It is a prospective, open-label, multi-center, single-arm study designed to confirm the safety and effectiveness of the HeartLight System during its commercial use. Participants will be monitored to evaluate the long-term results following catheter ablation procedures. The study seeks to provide additional data following a pivotal clinical study that initially validated the device's efficacy.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who are scheduled for catheter ablation due to symptomatic paroxysmal atrial fibrillation and have failed at least one anti-arrhythmic drug.

Not a fit: Patients who are in overall good health and do not meet the criteria for symptomatic paroxysmal atrial fibrillation may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a more effective treatment option for patients suffering from atrial fibrillation who have not responded to medication.

How similar studies have performed: Other studies have shown success with similar ablation approaches for atrial fibrillation, indicating a promising avenue for treatment.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years or older
* planned for catheter ablation due to symptomatic paroxysmal atrial fibrillation
* failure of at least one anti-arrhythmic drug
* others

Exclusion Criteria:

* overall good health as established by multiple criteria

Where this trial is running

Tucson, Arizona and 3 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Atrial Fibrillation
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.