Evaluating the effects of vitamin C on bone preservation after tooth extraction

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess the impact of adding vitamin C to autogenous demineralized dentin graft and i-PRF on marginal bone loss following tooth extraction. Participants will be divided into two groups: one receiving the graft with vitamin C and the other receiving the graft without it. The study will evaluate clinical and radiographic outcomes over a six-month follow-up period. The hypothesis is that vitamin C may enhance osteoblast activity and improve soft tissue quality, leading to better socket preservation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Inclusion criteria:

* ≥ 18 years of age.
* Single extraction of non-molar teeth with periodontally healthy adjacent teeth.
* Non-contributory medial history.
* Non- restorable teeth indicated for extraction.
* Requiring alveolar preservation after tooth extraction prior to placement of dental implant.
* Participants that are eligible for immediate implantation, yet having factors that are hindering these patients from immediate placement of an implant at the time of extraction (ex: Financial related factors - psychological psychological factors - time related factors).
* Cooperative patients who are willing to commit for 3 months follow up.

Exclusion Criteria:

* Pregnant female.
* Acute infection at extraction site.
* Systemic conditions affecting healing (e.g., diabetes, medications as bisphosphonates...)
* A participant who had radiotherapy or chemotherapy.
* Psychiatric patient, or with a learning disability, or unable to give consent.

Where it's running

• Faculty of Dentistry, Cairo University
  Cairo, Egypt Recruiting

Study contacts

• Principal investigator: Noha Barwa, Bachelor — Cairo University
• Study coordinator: Noha A Barwa, Bachelor
• Email: noha.ahmed@dentistry.cu.edu.eg
• Phone: +201116010759

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• Effects of Vitamin K2 on Bone Healing After Tooth Extraction

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.