Evaluating the effects of supraclavicular brachial plexus blocks on optic nerve sheath diameter
Evaluation of Supraclavicular Brachial Plexus Blocks At Different Volumes Under Ultrasound Guidance in Upper Extremity Surgery and Their Impact on Optic Nerve Sheath Diameter
This study is testing how different amounts of a specific nerve block used during upper limb surgery affect pain relief and eye pressure in patients.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 64 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Sponsor | Pamukkale University Academic / other |
| Locations | 1 site (Denizli, Pamukkale) |
| Trial ID | NCT06428461 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness and safety of supraclavicular brachial plexus blocks administered at different volumes under ultrasound guidance for patients undergoing upper limb surgery. It aims to assess anesthesia adequacy, side effects, complication rates, and postoperative pain relief effectiveness. Additionally, the study measures optic nerve sheath diameter using ultrasound to explore its relationship with intracranial pressure across varying block volumes. The research focuses on improving regional anesthesia techniques and understanding their impact on intracranial pressure.
Who should consider this trial
Good fit: Ideal candidates are patients aged 18 to 50 with planned surgeries on the finger, wrist, elbow joint, and distal region, classified as ASA I-II.
Not a fit: Patients with conditions that may cause increased intracranial pressure or severe cardiovascular issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance pain management techniques for upper limb surgeries while minimizing complications.
How similar studies have performed: Other studies have shown success with similar regional anesthesia techniques, but this specific approach is novel in its focus on optic nerve sheath diameter.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged between 18 and 50, of both genders, with planned surgery on the finger, wrist, elbow joint, and distal region, and classified as ASA I-II, will be included in the study. In this study, patients will be informed about the anesthesia method and the tests to be conducted, and those who consent will be asked to sign an informed consent form as voluntary participants. Exclusion Criteria: * Patients who do not accept the procedures and tests * Those with diseases that may cause increased intracranial pressure * Patients with severe heart failure * Patients with second or third degree atrioventricular block * Patients with unstable angina history * Patients with COPD and chronic asthma * Patients with a history of myocardial infarction (MI) within the last 6 weeks * Patients with a heart rate below 50 beats/min * Patients with systolic blood pressure below 90 mmHg * Patients with liver failure * Patients with kidney failure * Patients for whom supraclavicular block anatomically cannot be performed * Those with neurological or psychological diseases that make it difficult to assess the tests * Patients allergic to any of the study drugs * Pregnant women
Where this trial is running
Denizli, Pamukkale
- Pamukkale University — Denizli, Pamukkale, Turkey (Recruiting)
Study contacts
- Study coordinator: ismet çopur, MD
- Email: cpr.ismet@gmail.com
- Phone: 5318469060
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.