Evaluating the effects of probiotic yogurt on chronic constipation
Exploring the Potential Benefits of High-activity Probiotic Yogurt: a Randomized, Double-blind, Placebo-controlled Trial
NA · Wecare Probiotics Co., Ltd. · NCT06847919
This study tests if eating a special probiotic yogurt can help people with chronic constipation feel better over three weeks.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 84 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Wecare Probiotics Co., Ltd. (industry) |
| Locations | 1 site (Suzhou, Jiangsu) |
| Trial ID | NCT06847919 on ClinicalTrials.gov |
What this trial studies
This study evaluates the impact of a high-activity probiotic yogurt on alleviating symptoms of chronic constipation over a 21-day intervention period. Participants will be divided into two groups: one receiving the probiotic yogurt and the other receiving a yogurt control. The study will monitor changes in gut microbiota and any adverse reactions experienced by participants. Eligible candidates must meet specific criteria related to chronic constipation and overall health.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18-65 who meet the Rome IV criteria for chronic constipation.
Not a fit: Patients with systemic diseases, gastrointestinal disorders, or those who have recently taken certain medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a natural and effective dietary intervention for individuals suffering from chronic constipation.
How similar studies have performed: While there is some existing research on probiotics for gastrointestinal health, this specific approach with high-activity probiotic yogurt is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Meet the Rome IV diagnosis criteria for chronic constipation; 2. Patients who are able to understand clinical studies and are committed to complying with study requirements and procedures; 3. Age 18-65. - Exclusion Criteria: 1. Systemic (diabetes, autoimmune diseases, cancer), gastrointestinal or liver diseases known to be associated with alterations in the gut microbiota; 2. Patients who are pregnant or lactating; 3. have taken antimicrobials, probiotics, or drugs that inhibit stomach acid or gastrointestinal motility in the past 6 weeks; 4. Patients who changed their diet type during the study; 5. Patients who are allergic or intolerant to any component of the investigational product formulation; 6. Patients with cardiovascular, cerebrovascular, liver, kidney and hematopoietic system and other serious diseases and endocrine diseases, mental patients; 7. Stop taking the tested sample or add other drugs in the middle, unable to judge the efficacy or incomplete data; 8. short-term use of objects related to the function of the test, affecting the judgment of the result; 9. have been dieting, exercising excessively, taking weight loss medications or taking medications that may affect appetite in the past 3 months; 10. Current or past excessive use of alcohol, drugs, or supplements that may cause intestinal dysfunction or interfere with the evaluation of the efficacy of the study product -
Where this trial is running
Suzhou, Jiangsu
- Suzhou Ninth People's Hospital Suzhou Ninth Hospital affiliated to Soochow University — Suzhou, Jiangsu, China (RECRUITING)
Study contacts
- Study coordinator: Ying Jin, Doctor
- Email: sunny13211@sina.com
- Phone: 13375163966
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Chronic Constipation