Evaluating the effects of Intrapulmonary Percussive Ventilation on lung compliance in children on mechanical ventilation
The Effect of Intrapulmonary Percussive Ventilation (IPV) on Lung Compliance in Critically Ill Pediatric Patients Requiring Invasive Mechanical Ventilation.
This study is testing if a breathing treatment called Intrapulmonary Percussive Ventilation can help improve lung function in children on mechanical ventilation, especially those with severe breathing problems.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Ages | 0 Days to 18 Years |
| Sex | All |
| Sponsor | Northwell Health Academic / other |
| Locations | 1 site (New Hyde Park, New York) |
| Trial ID | NCT06836050 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess whether Intrapulmonary Percussive Ventilation (IPV) can enhance lung compliance in children who are receiving conventional invasive mechanical ventilation. It will investigate the effects of IPV on lung compliance at two time points: 15 minutes and 3 hours after treatment. The study will also compare the impact of IPV on patients with Pediatric Acute Respiratory Distress Syndrome (PARDS) against those without, and analyze the effects based on the severity of PARDS. Additionally, the incidence of any adverse effects related to IPV will be monitored.
Who should consider this trial
Good fit: Ideal candidates include children aged 18 years or younger who are on conventional mechanical ventilation and deemed safe for IPV by their medical team.
Not a fit: Patients who are unable to have accurate ventilator measurements taken will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved lung function and recovery in pediatric patients with respiratory distress.
How similar studies have performed: While the use of IPV is a standard practice in airway clearance, this specific observational approach to assess its impact on lung compliance in pediatric patients is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ≤18 years old on conventional intermittent mandatory ventilation in the PICU that the physician deems is a candidate for IPV Exclusion Criteria: * The inability to accurately obtain ventilator measurements
Where this trial is running
New Hyde Park, New York
- Cohen Children's Medical Center — New Hyde Park, New York, United States (Recruiting)
Study contacts
- Principal investigator: Todd Sweberg, MD — Northwell Health
- Study coordinator: Alexandra B Cummings, DO
- Email: acummingsdel@northwell.edu
- Phone: 631-223-6032
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.