Evaluating the effects of different platelet-rich fibrin techniques on gum tissue
Evaluation of the Effects of I-PRF and C-PRF on Gingival Phenotype
NA · Inonu University · NCT06964529
This study is testing whether two different methods of using platelet-rich fibrin can improve gum tissue in patients having surgery to fix their gums.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Inonu University (other) |
| Locations | 1 site (Malatya) |
| Trial ID | NCT06964529 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the impact of injectable platelet-rich fibrin (I-PRF) and concentrated platelet-rich fibrin (C-PRF) on gingival phenotype in patients undergoing mucogingival surgery using the VISTA technique. A total of 30 participants will be randomly assigned to receive either I-PRF or C-PRF, with treatments administered during surgery and at three subsequent sessions. The study will measure changes in gingival thickness and the width of keratinized gingiva using both manual and digital assessment methods at baseline, one month, and three months post-treatment. The goal is to determine which PRF technique is more effective for enhancing soft tissue outcomes.
Who should consider this trial
Good fit: Ideal candidates are systemically healthy individuals aged 18-65 with no recent periodontal surgery and a clinically healthy periodontium.
Not a fit: Patients with systemic diseases affecting healing, smokers, or those with poor oral hygiene may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve surgical outcomes and recovery for patients undergoing gum tissue procedures.
How similar studies have performed: Previous studies have shown promising results with the use of platelet-rich fibrin techniques in periodontal treatments, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Systemically healthy individuals aged 18-65 years No periodontal surgery in the last 6 monthsClinically healthy periodontium (no signs of active periodontal disease) Patient compliance and consent to participate Exclusion Criteria: Smoking Pregnancy or lactation Systemic diseases affecting healing (e.g., diabetes, immunosuppression) Use of anticoagulants or medications affecting soft tissue Poor oral hygiene or noncompliance
Where this trial is running
Malatya
- Inonu University Faculty of Dentistry — Malatya, Turkey (RECRUITING)
Study contacts
- Study coordinator: UMMU GULSUM OGE, RA
- Email: g.oge@inonu.edu.tr
- Phone: 05354404315
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Gingival Phenotype, Periodontal Soft Tissue, Width of Keratinized Gingiva, C-PRF, I-PRF, VISTA Technique