Evaluating the effects of cheese consumption on metabolism in middle-aged individuals
Assessment Metabolic Flexibility by Indirect Calorimetry and Circulating Metabolic Parameters in Middle-aged Individuals: The Nutritional Impact of Cheese From Extensive and Intensive Farming.
This study is testing how eating cheese from different farming methods affects metabolism in healthy middle-aged people.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 105 (estimated) |
| Ages | 45 Years to 65 Years |
| Sex | All |
| Sponsor | University of Cagliari Academic / other |
| Locations | 1 site (Monserrato, Cagliari) |
| Trial ID | NCT06012227 on ClinicalTrials.gov |
What this trial studies
This study aims to assess how consuming cheese from extensive versus intensive farming affects metabolic flexibility and lipid metabolism in healthy individuals aged 45 to 65. Participants will undergo a double-blind crossover intervention, consuming specific types of cheese for four weeks, followed by an eight-week washout period. Key measurements will include gene expression analysis, metabolic flexibility through indirect calorimetry, and body composition assessments. The study will involve 105 participants recruited from the UTIC cardiology unit of A.O.U.CA Cagliari in Italy.
Who should consider this trial
Good fit: Ideal candidates are healthy individuals aged 45 to 65 with a BMI under 27 and specific waist-to-hip ratio criteria.
Not a fit: Patients with metabolic diseases, competitive athletes, vegans, vegetarians, or those with food intolerances or allergies to the study foods may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into dietary impacts on metabolic health, potentially guiding nutritional recommendations for middle-aged individuals.
How similar studies have performed: While there is ongoing research into dietary impacts on metabolism, this specific approach focusing on cheese consumption and metabolic flexibility appears to be novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 45-65 years of age * BMI \< 27 * waist-to-hip ratio female\<0.85; male \< 0.98 Exclusion Criteria: * metabolic diseases * Physical activity of competitive nature * Vegans and vegetarians * Intolerances and allergies to the foods under study
Where this trial is running
Monserrato, Cagliari
- University of Cagliari — Monserrato, Cagliari, Italy (Recruiting)
Study contacts
- Study coordinator: Sebastiano Banni
- Email: banni@unica.it
- Phone: 070-6754128
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.