Evaluating the effects of cheese consumption on metabolism in middle-aged individuals
Official title: Assessment Metabolic Flexibility by Indirect Calorimetry and Circulating Metabolic Parameters in Middle-aged Individuals: The Nutritional Impact of Cheese From Extensive and Intensive Farming.
Run by University of Cagliari · NCT06012227 · Data updated 2026-11-12
This study is testing how eating cheese from different farming methods affects metabolism in healthy middle-aged people.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 45 Years to 65 Years |
| Sex | All |
| Enrollment | 105 (estimated) |
| Sponsor | University of Cagliari Academic / other |
| Locations | 1 site (Monserrato, Cagliari) |
| Status | Recruiting |
| Started | January 20, 2022 |
| Main results expected | July 27, 2023 |
| Study ends | December 20, 2026 |
| Registry record updated | August 30, 2023 |
| Trial ID | NCT06012227 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are healthy individuals aged 45 to 65 with a BMI under 27 and specific waist-to-hip ratio criteria.
✕Probably not a fit
Patients with metabolic diseases, competitive athletes, vegans, vegetarians, or those with food intolerances or allergies to the study foods may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to assess how consuming cheese from extensive versus intensive farming affects metabolic flexibility and lipid metabolism in healthy individuals aged 45 to 65. Participants will undergo a double-blind crossover intervention, consuming specific types of cheese for four weeks, followed by an eight-week washout period. Key measurements will include gene expression analysis, metabolic flexibility through indirect calorimetry, and body composition assessments. The study will involve 105 participants recruited from the UTIC cardiology unit of A.O.U.CA Cagliari in Italy.
Why it matters
Potential benefit: If successful, this study could provide insights into dietary impacts on metabolic health, potentially guiding nutritional recommendations for middle-aged individuals.
How similar studies have gone: While there is ongoing research into dietary impacts on metabolism, this specific approach focusing on cheese consumption and metabolic flexibility appears to be novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 45-65 years of age * BMI \< 27 * waist-to-hip ratio female\<0.85; male \< 0.98 Exclusion Criteria: * metabolic diseases * Physical activity of competitive nature * Vegans and vegetarians * Intolerances and allergies to the foods under study
Where it's running
-
University of Cagliari
Monserrato, Cagliari, Italy Recruiting
Study contacts
- Study coordinator: Sebastiano Banni
- Email: banni@unica.it
- Phone: 070-6754128
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.