Evaluating the effects of acromegaly on hand and foot dimensions and movement
Effects of Therapies in the Acromegaly Disease: Acral Morpho-functional Study
This study looks at how acromegaly affects the size and movement of hands and feet in patients to better understand the physical changes caused by the condition.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Istituto Auxologico Italiano Academic / other |
| Locations | 1 site (Milan) |
| Trial ID | NCT05964712 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the impact of acromegaly on the morphology and functionality of hands and feet in patients. Utilizing a 3D scanning system, the study will measure the geometrical and volumetric characteristics of the extremities in both newly diagnosed patients and those with varying disease statuses. Additionally, gait analysis will be performed to evaluate posture and balance control during walking. The study seeks to provide insights into the physical alterations caused by acromegaly and the effects of medical or surgical therapies.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older who are newly diagnosed with acromegaly or have different disease statuses.
Not a fit: Patients with cardiorespiratory, neurological, or musculoskeletal disorders, or those who have had previous orthopedic surgery or lower limb traumatic injuries may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of acromegaly's impact on physical function, potentially leading to improved management strategies for affected patients.
How similar studies have performed: While there have been studies on acromegaly, this specific approach using advanced 3D scanning and gait analysis is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * De novo patients with acromegaly (group # 1), diagnosed according to Endocrine Society guidelines, * Age equal to18 years or older * Acromegalic patients with different disease status (group #2) * Age equal to18 years or older Exclusion Criteria: * Cardiorespiratory, neurological or musculoskeletal disorder * Previous orthopaedic surgery * Previous lower limbs traumatic injuries
Where this trial is running
Milan
- Istituto Auxologico Italiano IRCCS San Luca — Milan, Italy (Recruiting)
Study contacts
- Principal investigator: Giovanni Vitale — Istituto Auxologico Italiano IRCCS
- Study coordinator: Sara Farina, Doctor
- Email: sara.farina@unimi.it
- Phone: +393386822298
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.