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Clinical trial Recruiting at 1 site Observational Ages 18 and up

Evaluating the effectiveness of uncovered duodenal prostheses for treating duodenal stenosis

Official title: Evaluation of the Efficacy of Duodenal Prostheses Not Covered Over 6 Years

Run by Institut Paoli-Calmettes · NCT03463668 · Data updated 2026-11-12

This study is testing if uncovered metal tubes can help people with blocked intestines due to tumors feel better and how long they work before more treatment is needed.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment200 (estimated)
SponsorInstitut Paoli-Calmettes
Academic / other
Locations1 site (Marseille, Bouches Du Rhone)
StatusRecruiting
StartedDecember 22, 2017
Main results expectedDecember 2029
Study endsDecember 2029
Registry record updatedMarch 13, 2018
Trial IDNCT03463668 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients with symptomatic duodenal stenosis due to unresectable tumors who received uncovered duodenal prostheses between 2010 and 2017.

Probably not a fit

Patients with benign stenosis or those who have received covered metallic duodenal prostheses will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the efficacy of uncovered metal duodenal prostheses in patients with symptomatic duodenal stenosis caused by digestive or non-digestive neoplasia. The study will evaluate the technical success rate and the duration of effectiveness of these prostheses, which have been the first-line treatment since the 2000s. It will also explore the potential need for surgical interventions or endoscopic procedures in cases where prostheses are used. Data will be collected from patients who received these prostheses between 2010 and 2017.

Why it matters

Potential benefit: If successful, this study could provide insights into the long-term effectiveness of duodenal prostheses, improving treatment strategies for patients with duodenal stenosis.

How similar studies have gone: While the use of duodenal prostheses has been established, this study aims to provide new insights into their long-term efficacy, making it a valuable addition to existing knowledge rather than a completely novel approach.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Any symptomatic duodenal stenosis with symptomatic duodenal duodenal prosthesis between 2010 and 2017.

Exclusion Criteria:

* Benign stenosis or covered metallic duodenal prosthesis (usually indicated for benign disease)

Where it's running

  • Institut Paoli Calmettes
    Marseille, Bouches Du Rhone, France     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.