Evaluating the effectiveness of family therapy for suicidal young adults
Official title: Targeting Suicidality in Young Adults: a Randomized, Controlled Pragmatic, Multicentre Trial Evaluating the (Cost)-Effectiveness of Attachment Based Family Therapy Compared to Treatment as Usual
Run by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · NCT05965622 · Data updated 2026-11-12
This study is testing whether a special family therapy can help young adults aged 18 to 25 who are having suicidal thoughts feel better compared to standard treatment.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 25 Years |
| Sex | All |
| Enrollment | 138 (estimated) |
| Sponsor | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Academic / other |
| Locations | 13 sites (Tongeren, Limburg and 12 other locations) |
| Status | Recruiting |
| Started | October 5, 2023 |
| Main results expected | November 15, 2025 |
| Study ends | November 14, 2026 |
| Registry record updated | August 22, 2024 |
| Trial ID | NCT05965622 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are young adults aged 18 to 25 who score above 31 on the Suicidal Ideation Questionnaire Junior and have a participating primary caregiver.
✕Probably not a fit
Patients with severe substance use disorders, psychotic features, or significant cognitive impairments may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to assess the (cost-)effectiveness of Attachment Based Family Therapy (ABFT) compared to Treatment As Usual (TAU) for young adults aged 18 to 25 who exhibit suicidal ideation. The study will involve a randomized controlled trial design, where participants will receive either ABFT alongside TAU or just TAU. The primary focus is on reducing suicidal thoughts and behaviors, while secondary objectives include evaluating cost-effectiveness, family functioning, and attachment improvements. The intervention will last approximately 16 weeks, with weekly sessions aimed at strengthening parent-child relationships.
Why it matters
Potential benefit: If successful, this approach could significantly reduce suicidal ideation and behaviors among young adults while improving family dynamics.
How similar studies have gone: While there is limited research on family-based treatments for suicidality in young adults, emerging evidence suggests that involving family members can enhance treatment outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged between 18 and 25. * A score above 31 on the SIQ-JR (the cut-off for suicidality). * Have at least one primary parent or caregiver that participates in the assessment and treatment. This could be a biological parent, stepparent, grandparent, other relative, or a foster parent. Exclusion Criteria: * Other DSM-5 disorders: substance dependency: severe alcohol or cannabis use disorder, all other substances: modest or severe substance use disorder. * Severe conduct disorder. * Evidence of psychotic features or prior psychosis (assessed with the SCID-5-S). * Severe cognitive impairment (e.g., mental retardation, severe developmental disorders) as evidenced by educational records, parental report and/or clinical impression. * Other circumstances that might affect participation (e.g., severe medical disorder, relocation).
Where it's running
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Prakijkt ConnectUs
Tongeren, Limburg, Belgium Recruiting -
UPC KU Leuven, campus Kortenberg
Kortenberg, Vlaams-Brabant, Belgium Recruiting -
STUVO Psychologen en Psychiaters
Leuven, Vlaams-Brabant, Belgium Recruiting -
Praktijk Annemie Uyttersprot
Merchtem, Vlaams-Brabant, Belgium Recruiting -
GGzE
Eindhoven, North Brabant, Netherlands Recruiting -
GGZ Oost Brabant
Oss, North Brabant, Netherlands Recruiting
Show 7 more locations
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Arkin
Amsterdam, North Holland, Netherlands Recruiting -
Kenter Jeugdhulp
Santpoort-Noord, North Holland, Netherlands Recruiting -
GGz Centraal
Amersfoort, Utrecht, Netherlands Recruiting -
UGent Centrum Kind en Adolescent
Ghent, Oost-Vlaanderen, Belgium Not yet recruiting -
PraxisP
Leuven, Vlaams-Brabant, Belgium Not yet recruiting -
Academisch Medisch Centrum
Amsterdam, North Holland, Netherlands Not yet recruiting -
Levvel
Amsterdam, North Holland, Netherlands Not yet recruiting
Study contacts
- Principal investigator: Claudi Bockting, professor — Academic Medical Center (AMC)
- Study coordinator: Claudi LH Bockting, Professor
- Email: c.l.bockting@amsterdamumc.nl
- Phone: +3120-8913600
Similar studies
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This observational study looks at whether financial hardship and social isolation are linked to depression, suicidal thoughts, and loneliness among French university students.
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Ketamine with DBT for suicidality in adults with treatment-resistant depression or bipolar disorder and BPD
This study tests whether four ketamine infusions plus Dialectical Behavioural Therapy can more quickly reduce suicidal thoughts in adults with Borderline Personality Disorder and treatment-resistant depression or bipolar disorder.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.