Clinical trial Recruiting at 9 sites Interventional Ages 18 to 25

Evaluating the effectiveness of family therapy for suicidal young adults

Official title: Targeting Suicidality in Young Adults: a Randomized, Controlled Pragmatic, Multicentre Trial Evaluating the (Cost)-Effectiveness of Attachment Based Family Therapy Compared to Treatment as Usual

Run by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · NCT05965622 · Data updated 2026-11-12

This study is testing whether a special family therapy can help young adults aged 18 to 25 who are having suicidal thoughts feel better compared to standard treatment.

More Suicidal Ideation trials

Quick facts

Study typeInterventional
Ages18 Years to 25 Years
SexAll
Enrollment138 (estimated)
SponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Academic / other
Locations13 sites (Tongeren, Limburg and 12 other locations)
StatusRecruiting
StartedOctober 5, 2023
Main results expectedNovember 15, 2025
Study endsNovember 14, 2026
Registry record updatedAugust 22, 2024
Trial IDNCT05965622 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are young adults aged 18 to 25 who score above 31 on the Suicidal Ideation Questionnaire Junior and have a participating primary caregiver.

Probably not a fit

Patients with severe substance use disorders, psychotic features, or significant cognitive impairments may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to assess the (cost-)effectiveness of Attachment Based Family Therapy (ABFT) compared to Treatment As Usual (TAU) for young adults aged 18 to 25 who exhibit suicidal ideation. The study will involve a randomized controlled trial design, where participants will receive either ABFT alongside TAU or just TAU. The primary focus is on reducing suicidal thoughts and behaviors, while secondary objectives include evaluating cost-effectiveness, family functioning, and attachment improvements. The intervention will last approximately 16 weeks, with weekly sessions aimed at strengthening parent-child relationships.

Why it matters

Potential benefit: If successful, this approach could significantly reduce suicidal ideation and behaviors among young adults while improving family dynamics.

How similar studies have gone: While there is limited research on family-based treatments for suicidality in young adults, emerging evidence suggests that involving family members can enhance treatment outcomes.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged between 18 and 25.
* A score above 31 on the SIQ-JR (the cut-off for suicidality).
* Have at least one primary parent or caregiver that participates in the assessment and treatment. This could be a biological parent, stepparent, grandparent, other relative, or a foster parent.

Exclusion Criteria:

* Other DSM-5 disorders: substance dependency: severe alcohol or cannabis use disorder, all other substances: modest or severe substance use disorder.
* Severe conduct disorder.
* Evidence of psychotic features or prior psychosis (assessed with the SCID-5-S).
* Severe cognitive impairment (e.g., mental retardation, severe developmental disorders) as evidenced by educational records, parental report and/or clinical impression.
* Other circumstances that might affect participation (e.g., severe medical disorder, relocation).

Where it's running

  • Prakijkt ConnectUs
    Tongeren, Limburg, Belgium
    Recruiting
  • UPC KU Leuven, campus Kortenberg
    Kortenberg, Vlaams-Brabant, Belgium
    Recruiting
  • STUVO Psychologen en Psychiaters
    Leuven, Vlaams-Brabant, Belgium
    Recruiting
  • Praktijk Annemie Uyttersprot
    Merchtem, Vlaams-Brabant, Belgium
    Recruiting
  • GGzE
    Eindhoven, North Brabant, Netherlands
    Recruiting
  • GGZ Oost Brabant
    Oss, North Brabant, Netherlands
    Recruiting
Show 7 more locations
  • Arkin
    Amsterdam, North Holland, Netherlands
    Recruiting
  • Kenter Jeugdhulp
    Santpoort-Noord, North Holland, Netherlands
    Recruiting
  • GGz Centraal
    Amersfoort, Utrecht, Netherlands
    Recruiting
  • UGent Centrum Kind en Adolescent
    Ghent, Oost-Vlaanderen, Belgium
    Not yet recruiting
  • PraxisP
    Leuven, Vlaams-Brabant, Belgium
    Not yet recruiting
  • Academisch Medisch Centrum
    Amsterdam, North Holland, Netherlands
    Not yet recruiting
  • Levvel
    Amsterdam, North Holland, Netherlands
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.