Evaluating the effectiveness and safety of AD-209 for hypertension

A Multicenter, Randomized, Double-blind, Active-control, Phase III Study to Evaluate the Efficacy and Safety of AD-209 in Patients With Essential Hypertension

Phase 3 Interventional Addpharma Inc. · NCT06348576

This study is testing a new medication called AD-209 to see if it can safely lower blood pressure in people with high blood pressure.

Quick facts

PhasePhase 3
Study typeInterventional
Enrollment280 (estimated)
Ages19 Years and up
SexAll
SponsorAddpharma Inc. Industry-sponsored
Locations1 site (Seoul)
Trial IDNCT06348576 on ClinicalTrials.gov

What this trial studies

This study aims to assess the efficacy and safety of a new medication, AD-209, in patients with essential hypertension. Participants will receive either AD-209, a related compound AD-2091, or a placebo to compare outcomes. The study will involve monitoring blood pressure levels and any side effects experienced by participants over the course of the trial. The goal is to determine if AD-209 can provide a safe and effective treatment option for managing hypertension.

Who should consider this trial

Good fit: Ideal candidates for this study are adults diagnosed with essential hypertension who can provide informed consent.

Not a fit: Patients with orthostatic hypotension or those experiencing related symptoms may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could offer a new effective option for patients struggling with hypertension.

How similar studies have performed: While there have been various studies on hypertension treatments, the specific approach with AD-209 is novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Signed informed consent
* Other inclusions applied

Exclusion Criteria:

* Orthostatic hypotension with symptom
* Other exclusions applied

Where this trial is running

Seoul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hypertension,Essential
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.