Evaluating the effect of non-carious cervical lesions on root coverage outcomes
The Influence of Non-Carious Cervical Lesions on Root Coverage by Means of Coronally Advanced Flap and a Connective Tissue Graft: A Prospective Cohort Study
This study tests how non-carious cervical lesions affect the success of root coverage treatment for people with gum recession by comparing two different approaches to surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 56 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Universitat Internacional de Catalunya Academic / other |
| Locations | 1 site (Barcelona) |
| Trial ID | NCT06438094 on ClinicalTrials.gov |
What this trial studies
This prospective cohort study aims to assess how non-carious cervical lesions (NCCLs) affect the success of root coverage therapy in patients with gingival recession. It compares two groups: one where the cementoenamel junction (CEJ) is reconstructed before surgery and another where the CEJ is visible. The study will evaluate clinical outcomes, dentin sensitivity, and patient satisfaction after treatment. This is the first study to utilize a specific classification system to guide periodontal-restorative procedures.
Who should consider this trial
Good fit: Ideal candidates include systemically healthy individuals over 18 with specific types of gingival recession associated with NCCLs.
Not a fit: Patients who are pregnant, smoke heavily, or have metabolic diseases affecting healing may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve treatment strategies for patients with gingival recession associated with NCCLs, leading to better clinical outcomes and patient satisfaction.
How similar studies have performed: While this approach is novel in its specific application, similar studies have shown promising results in root coverage therapies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Systemically healthy individuals older than 18 years old; * Healthy periodontal status according to the AAP/EFP definition; * Full-mouth plaque (FMPS) and bleeding scores (FMBS) ≤ 20%; * At least one facial RT1 GR in single-rooted teeth with a minimum depth of 2 mm, associated with a NCCL; * No history of periodontal surgery at the experimental site(s). Exclusion Criteria: * Pregnancy or lactation; * Self-reported smoking ≥10 cigarettes/day; * Metabolic diseases that negatively affect soft tissue healing (i.e., diabetes mellitus); * Any medication that may interfere with wound healing; * Prosthetic crown at experimental teeth; * Ongoing orthodontic therapy.
Where this trial is running
Barcelona
- BLASI Clínica Dental Barcelona — Barcelona, Spain (Recruiting)
Study contacts
- Principal investigator: José Nart — Universitat Internacional de Catalunya
- Study coordinator: Gonzalo Blasi
- Email: gonzaloblasi@uic.es
- Phone: 620387688
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.