Evaluating the effect of dental screenings on endocarditis risk in TAVI patients
Official title: Impact of Targeted Preoperative Dental Screening on Post-procedural Risk of Infective Endocarditis in Patients Undergoing Transcatheter Aortic Valve Implantation: a Prospective Observational Study
Run by Odense University Hospital · NCT06330766 · Data updated 2026-11-12
This study looks at whether changing dental check-up rules can lower the risk of heart infections in patients getting a new heart valve through a procedure called TAVI.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Odense University Hospital Academic / other |
| Locations | 1 site (Odense, Odense) |
| Status | Recruiting |
| Started | January 1, 2020 |
| Main results expected | January 1, 2027 |
| Study ends | January 1, 2027 |
| Registry record updated | October 21, 2026 |
| Trial ID | NCT06330766 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients scheduled to undergo Transcatheter Aortic Valve Implantation.
✕Probably not a fit
Patients who are not undergoing TAVI or those with urgent surgical needs may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study at Odense University Hospital examines the impact of changing preoperative dental screening protocols on the risk of infective endocarditis (IE) in patients undergoing Transcatheter Aortic Valve Implantation (TAVI). The study compares the incidence of IE before and after the implementation of a targeted dental screening approach, which was modified from a mandatory protocol. By analyzing registry data, the researchers aim to provide insights into the effectiveness of dental screenings in reducing IE risk among this patient population.
Why it matters
Potential benefit: If successful, this study could lead to improved guidelines for dental screening practices, potentially reducing the risk of infective endocarditis in TAVI patients.
How similar studies have gone: Previous studies have shown mixed results regarding the effectiveness of dental screenings in preventing infective endocarditis, making this approach both relevant and necessary for further investigation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing TAVI Exclusion Criteria: * None
Where it's running
-
Odense University Hospital, Cardiology Department
Odense, Odense, Denmark Recruiting
Study contacts
- Principal investigator: Jordi S Dahl, MD,PhD,DMSc — Odense University Hospital
- Study coordinator: Jordi S Dahl, MD,PhD,DMSc
- Email: Jordi.Sanchez.Dahl@rsyd.dk
- Phone: 004524638899
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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This study is testing whether changing dental screening procedures can lower the risk of infective endocarditis in patients having heart valve surgery.
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This study is testing how often new heart conduction problems happen after aortic valve replacement and whether they can be fixed, focusing on patients who develop specific issues after the procedure.
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Barts Endocarditis Registry
This registry collects health, imaging, microbiology, treatment, and outcome information from adults with infective endocarditis seen at Barts Heart Centre to learn which approaches work best.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.