Evaluating the effect of dental screenings on endocarditis risk in TAVI patients
Impact of Targeted Preoperative Dental Screening on Post-procedural Risk of Infective Endocarditis in Patients Undergoing Transcatheter Aortic Valve Implantation: a Prospective Observational Study
Odense University Hospital · NCT06330766
This study looks at whether changing dental check-up rules can lower the risk of heart infections in patients getting a new heart valve through a procedure called TAVI.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Odense University Hospital (other) |
| Locations | 1 site (Odense) |
| Trial ID | NCT06330766 on ClinicalTrials.gov |
What this trial studies
This observational study at Odense University Hospital examines the impact of changing preoperative dental screening protocols on the risk of infective endocarditis (IE) in patients undergoing Transcatheter Aortic Valve Implantation (TAVI). The study compares the incidence of IE before and after the implementation of a targeted dental screening approach, which was modified from a mandatory protocol. By analyzing registry data, the researchers aim to provide insights into the effectiveness of dental screenings in reducing IE risk among this patient population.
Who should consider this trial
Good fit: Ideal candidates for this study are patients scheduled to undergo Transcatheter Aortic Valve Implantation.
Not a fit: Patients who are not undergoing TAVI or those with urgent surgical needs may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved guidelines for dental screening practices, potentially reducing the risk of infective endocarditis in TAVI patients.
How similar studies have performed: Previous studies have shown mixed results regarding the effectiveness of dental screenings in preventing infective endocarditis, making this approach both relevant and necessary for further investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing TAVI Exclusion Criteria: * None
Where this trial is running
Odense
- Odense University Hospital, Cardiology Department — Odense, Denmark (RECRUITING)
Study contacts
- Principal investigator: Jordi S Dahl, MD,PhD,DMSc — Odense University Hospital
- Study coordinator: Jordi S Dahl, MD,PhD,DMSc
- Email: Jordi.Sanchez.Dahl@rsyd.dk
- Phone: 004524638899
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Transcatheter Aortic Valve Implantation, Dental, Endocarditis, Transcatheter aortic valve implantation, TAVI, Preoperative dental screening, Infectious endocarditis