Clinical trial Recruiting at 1 site Observational Ages 18 and up

Evaluating the effect of dental screenings on endocarditis risk in TAVI patients

Official title: Impact of Targeted Preoperative Dental Screening on Post-procedural Risk of Infective Endocarditis in Patients Undergoing Transcatheter Aortic Valve Implantation: a Prospective Observational Study

Run by Odense University Hospital · NCT06330766 · Data updated 2026-11-12

This study looks at whether changing dental check-up rules can lower the risk of heart infections in patients getting a new heart valve through a procedure called TAVI.

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Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1000 (estimated)
SponsorOdense University Hospital
Academic / other
Locations1 site (Odense, Odense)
StatusRecruiting
StartedJanuary 1, 2020
Main results expectedJanuary 1, 2027
Study endsJanuary 1, 2027
Registry record updatedOctober 21, 2026
Trial IDNCT06330766 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients scheduled to undergo Transcatheter Aortic Valve Implantation.

Probably not a fit

Patients who are not undergoing TAVI or those with urgent surgical needs may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study at Odense University Hospital examines the impact of changing preoperative dental screening protocols on the risk of infective endocarditis (IE) in patients undergoing Transcatheter Aortic Valve Implantation (TAVI). The study compares the incidence of IE before and after the implementation of a targeted dental screening approach, which was modified from a mandatory protocol. By analyzing registry data, the researchers aim to provide insights into the effectiveness of dental screenings in reducing IE risk among this patient population.

Why it matters

Potential benefit: If successful, this study could lead to improved guidelines for dental screening practices, potentially reducing the risk of infective endocarditis in TAVI patients.

How similar studies have gone: Previous studies have shown mixed results regarding the effectiveness of dental screenings in preventing infective endocarditis, making this approach both relevant and necessary for further investigation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients undergoing TAVI

Exclusion Criteria:

* None

Where it's running

  • Odense University Hospital, Cardiology Department
    Odense, Odense, Denmark
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.