Evaluating the anion gap's ability to predict heart events in STEMI patients

The Prognostic Value of Anion Gap in Predicting Major Adverse Cardiovascular Events Among Patients With ST-Segment Elevation Myocardial Infarction

Observational Universitas Diponegoro · NCT06586424

This study is testing if the anion gap can help predict serious heart problems in patients who have had a heart attack and received treatment to open their blocked arteries.

Quick facts

Study typeObservational
Enrollment80 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorUniversitas Diponegoro Academic / other
Locations1 site (Semarang, Central of Java)
Trial IDNCT06586424 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess how well the anion gap can predict major adverse cardiovascular events in patients diagnosed with ST-segment elevation myocardial infarction (STEMI) who have undergone primary percutaneous coronary intervention (PPCI). Researchers will analyze secondary data collected from hospital registries, including demographic information, clinical presentations, laboratory results, and angiography findings. The data will be processed using IBM SPSS Statistics v26 to identify any correlations between anion gap levels and patient outcomes.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 70 diagnosed with STEMI who have undergone PPCI.

Not a fit: Patients with a history of heart failure, cardiogenic shock, infections at presentation, pregnancy, or other causes of high anion gap levels may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve risk stratification and management of STEMI patients, potentially leading to better patient outcomes.

How similar studies have performed: While the prognostic value of the anion gap has been explored in various contexts, this specific application in STEMI patients is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults with 18 - 70 years old with diagnosis of STEMI who underwent PPCI

Exclusion Criteria:

* History of heart failure due to any causes
* Cardiogenic shock before PPCI
* Any infection at the time of presentation
* Pregnant woman
* Other causes of high anion gap levels such as chronic kidney disease, metabolic acidosis, etc

Where this trial is running

Semarang, Central of Java

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions ST-segment Elevation Myocardial Infarctionanion gapmajor adverse cardiovascular eventsst-segment elevation myocardial infarction
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.