Evaluating the anatomy of thumb tendons in osteoarthritis
Anatomical Evaluation of the APL and FCR Tendons in Thumb CMC Joint in Relation to Osteophytes Formation of the Trapezium and Osteoarthritis.
This study looks at the thumb tendons in older adults with osteoarthritis to see how their structure and nerve connections might affect joint stability and the development of bone growths.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 20 (estimated) |
| Ages | 50 Years to 90 Years |
| Sex | All |
| Sponsor | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau Academic / other |
| Locations | 2 sites (Barcelona and 1 other locations) |
| Trial ID | NCT05626192 on ClinicalTrials.gov |
What this trial studies
This observational study aims to analyze the anatomical features and sensory innervation of the accessory abductor pollicis longus (APL) tendons in the thumb carpometacarpal (CMC) joint, particularly in relation to thumb osteoarthritis. Using immunohistochemical methods, the study will investigate the presence of mechanoreceptors and sensory corpuscles that may contribute to joint stability. The research focuses on adults aged 50 to 90 years, examining how tendon insertions and ligaments affect the development of osteophytes and osteoarthritis in the thumb CMC joint.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 50 to 90 years with thumb osteoarthritis.
Not a fit: Patients younger than 50 or older than 90 years may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of thumb osteoarthritis and lead to improved treatment strategies.
How similar studies have performed: While similar studies have explored sensory innervation in other joints, this specific investigation into the thumb CMC joint is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Specimens: Adults from 50 to 90 years. Exclusion Criteria: * Specimens: younger than 50 or older than 90 years.
Where this trial is running
Barcelona and 1 other locations
- Claudia Erika Delgado Espinoza — Barcelona, Spain (Recruiting)
- Hospital de la Santa Creu i Sant Pau — Barcelona, Spain (Recruiting)
Study contacts
- Principal investigator: Claudia Lamas, MD, Ph D — Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
- Study coordinator: Claudia Lamas, MD, Ph D
- Email: clamasg@santpau.cat
- Phone: 935537032
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.