Evaluating the ALPS Proximal Humerus Plating System for shoulder fractures

Clinical Outcomes of the ALPS Proximal Humerus Plating System

Vanderbilt University Medical Center · NCT03328650

This study is testing how well a new shoulder plate works for people with shoulder fractures by looking at their strength, movement, and pain levels after treatment.

Quick facts

Study typeObservational
Enrollment150 (estimated)
Ages18 Years and up
SexAll
SponsorVanderbilt University Medical Center (other)
Locations1 site (Nashville, Tennessee)
Trial IDNCT03328650 on ClinicalTrials.gov

What this trial studies

This observational study aims to document the clinical outcomes and performance of the A.L.P.S® Proximal Humerus Plating System in patients with proximal humeral fractures. It involves physical assessments to measure shoulder strength and range of motion, as well as physician evaluations of radiographs. Additionally, patient-reported outcomes regarding pain levels, functional capabilities, and work or leisure restrictions will be collected. The study will also track any revisions, complications, and adverse events associated with the treatment.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older with a proximal humerus fracture requiring surgical intervention using the A.L.P.S Proximal Humerus Plating System.

Not a fit: Patients under 18, those with infections or severe psychiatric disorders, and individuals who do not speak English may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve treatment strategies for proximal humeral fractures, leading to better patient outcomes.

How similar studies have performed: While this study focuses on a specific plating system, similar approaches in evaluating surgical interventions for fractures have shown promising results in the past.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients who present with a proximal humerus fracture requiring primary or revision ORIF using A.L.P.S Proximal Humerus Plating System
* Patients who present with a proximal humerus fracture that involves the metaphysis
* 18 years or older

Exclusion Criteria:

* Patients under the age of 18
* Patients who have an infection, sepsis, or osteomyelitis
* Patients who are unwilling to take part in study, have documented psychiatric disorder that limits ability to consent and maintain follow-up, or who may have severe problems maintaining follow-up (e.g. patients who are prisoners, homeless, intellectually changed without adequate family support)
* Patients who do not speak English (do to unavailability of non-English surveys)
* Patients who have known risk factors of pathologic fractures (e.g. bone metastasis)
* Patients who have received treatment for osteoporosis (e.g. bisphosphonate) within the last 5 years or whose treatment lasted longer than 5 years
* Patients who have Type 1 diabetes
* Patients who have other bone disease (e.g. osteogenesis imperfecta, Paget's disease, thyroid disease, Vitamin D deficiency, hyperparathyroidism)
* Patients that have a history of cancer, abnormal serum calcium, or chronic steroid use

Where this trial is running

Nashville, Tennessee

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Proximal Humeral Fracture

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.