Evaluating the alignment of the Atlas in chronic whiplash
Official title: Assessment of the Alignment of the Atlas and Surrounding Tissues in Chronic Whiplash Associated Disorder
Run by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · NCT06413667 · Data updated 2026-11-12
This study is trying to see how the position of a specific neck bone relates to pain and movement in people with chronic whiplash compared to healthy individuals and those with tension headaches.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 90 (estimated) |
| Sponsor | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Academic / other |
| Locations | 1 site (Amsterdam) |
| Status | Recruiting |
| Started | April 8, 2024 |
| Main results expected | December 30, 2025 |
| Study ends | December 1, 2026 |
| Registry record updated | May 14, 2024 |
| Trial ID | NCT06413667 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals aged 18-75 with a diagnosis of chronic whiplash-associated disorder (grades 1 or 2), tension headaches, or healthy controls.
✕Probably not a fit
Patients with a history of claustrophobia or those unable to provide informed consent may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to assess the position and alignment of the Atlas (C1) and surrounding tissues in patients with chronic whiplash-associated disorder (WAD) compared to healthy controls and those with tension headaches. Utilizing advanced imaging technologies, the research will explore the relationship between Atlas alignment and various factors such as pain intensity, neck movement limitations, and overall quality of life. The study seeks to provide insights into the complexities of chronic WAD, which often presents diagnostic challenges for healthcare providers.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and treatment options for patients suffering from chronic whiplash-associated disorder.
How similar studies have gone: While studies have explored aspects of whiplash injuries, this specific focus on Atlas alignment in chronic WAD is relatively novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Participants fulfilling the criteria mentioned below: Control participants In order to be eligible to participate in this study, a participant must meet the following criteria: * Healthy individuals * Ability to follow test instructions * Aged between 18 - 75 years Chronic Whiplash Associated Disorder In order to be eligible to participate in this study, a participant must meet the following criteria: * Healthy individuals * Ability to follow test instructions * WAD 1 or 2 Diagnosis * Aged between 18 - 75 years Tension headache In order to be eligible to participate in this study, a participant must meet the following criteria: * Healthy individuals * Ability to follow test instructions * Diagnosis Tension headache * Aged between 18 -75 years Exclusion Criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: * Inability to provide informed consent * Have a history of claustrophobia * Patient/ participant is not eligible to follow instructions * Contra-indication for MRI (e.g., pacemaker, claustrophobia) * Being under investigation for non-diagnosed disease at the time of investigation
Where it's running
-
Amsterdam UMC
Amsterdam, Netherlands Recruiting
Study contacts
- Study coordinator: Nederveen
- Email: a.j.nederveen@amsterdamumc.nl
- Phone: +31 20 5629338
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Ear-based vagus nerve stimulation for chronic whiplash-associated disorder
This study will test whether mild electrical stimulation of the vagus nerve through the ear can help people with chronic whiplash-associated disorder reduce pain and stress-related symptoms.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.