Evaluating the alignment of the Atlas in chronic whiplash

Assessment of the Alignment of the Atlas and Surrounding Tissues in Chronic Whiplash Associated Disorder

Observational Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · NCT06413667

This study is trying to see how the position of a specific neck bone relates to pain and movement in people with chronic whiplash compared to healthy individuals and those with tension headaches.

Quick facts

Study typeObservational
Enrollment90 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Academic / other
Locations1 site (Amsterdam)
Trial IDNCT06413667 on ClinicalTrials.gov

What this trial studies

This study aims to assess the position and alignment of the Atlas (C1) and surrounding tissues in patients with chronic whiplash-associated disorder (WAD) compared to healthy controls and those with tension headaches. Utilizing advanced imaging technologies, the research will explore the relationship between Atlas alignment and various factors such as pain intensity, neck movement limitations, and overall quality of life. The study seeks to provide insights into the complexities of chronic WAD, which often presents diagnostic challenges for healthcare providers.

Who should consider this trial

Good fit: Ideal candidates include individuals aged 18-75 with a diagnosis of chronic whiplash-associated disorder (grades 1 or 2), tension headaches, or healthy controls.

Not a fit: Patients with a history of claustrophobia or those unable to provide informed consent may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and treatment options for patients suffering from chronic whiplash-associated disorder.

How similar studies have performed: While studies have explored aspects of whiplash injuries, this specific focus on Atlas alignment in chronic WAD is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria: Participants fulfilling the criteria mentioned below:

Control participants In order to be eligible to participate in this study, a participant must meet the following criteria:

* Healthy individuals
* Ability to follow test instructions
* Aged between 18 - 75 years

Chronic Whiplash Associated Disorder

In order to be eligible to participate in this study, a participant must meet the following criteria:

* Healthy individuals
* Ability to follow test instructions
* WAD 1 or 2 Diagnosis
* Aged between 18 - 75 years

Tension headache

In order to be eligible to participate in this study, a participant must meet the following criteria:

* Healthy individuals
* Ability to follow test instructions
* Diagnosis Tension headache
* Aged between 18 -75 years

Exclusion Criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study:

* Inability to provide informed consent
* Have a history of claustrophobia
* Patient/ participant is not eligible to follow instructions
* Contra-indication for MRI (e.g., pacemaker, claustrophobia)
* Being under investigation for non-diagnosed disease at the time of investigation

Where this trial is running

Amsterdam

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic Whiplash Associated DisorderAtlasMRI
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.