Evaluating the accuracy of robotic cranial biopsies

Diagnostic Accuracy of Robotically Assisted Cranial Biopsies Using Cirq Active Cranial and Automatic Image Registration

Observational Brainlab AG · NCT05891002

This study is testing how well a robotic system can perform brain biopsies on patients with brain tumors to see if it can accurately diagnose their condition.

Quick facts

Study typeObservational
Enrollment50 (estimated)
Ages18 Years and up
SexAll
SponsorBrainlab AG Industry-sponsored
Locations1 site (Angers)
Trial IDNCT05891002 on ClinicalTrials.gov

What this trial studies

This observational study assesses the accuracy of the Cirq® Robotic Alignment Module Cranial in performing biopsies on patients with intracranial neoplasms. The study aims to achieve a diagnostic yield of at least 90% by measuring the accuracy of the biopsy needle within a specific intraoperative workflow. Patients will undergo standard care procedures while the robotic system's performance is evaluated in a clinical setting. The study focuses on the compatibility of the robotic system with existing clinical workflows and the accuracy of automatic image registration.

Who should consider this trial

Good fit: Ideal candidates include patients with an intracranial lesion requiring a diagnostic stereotactic biopsy.

Not a fit: Patients who are pregnant or have contraindications to anesthesia, surgery, or imaging procedures will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the precision of cranial biopsies, leading to better diagnostic outcomes for patients with brain tumors.

How similar studies have performed: While this study is focused on a specific robotic system, similar robotic-assisted biopsy approaches have shown promise in improving diagnostic accuracy in previous studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Intracranial lesion and the indication for a diagnostic stereotactic biopsy validated by the neurosurgical staff
* Ability to consent to the procedure

Exclusion Criteria:

* Pregnancy
* Contraindications on narcosis, operation, CT scan, MRI scan and/or Gadolinium contrast agent

Where this trial is running

Angers

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Intracranial Neoplasm
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.