Evaluating the accuracy of normal-looking bladder mucosa during cystoscopy for detecting hidden tumors

Can Narrow-band Imaging Detect CIS/Tumor in Normally Looking Bladder Mucosa on White Light Cystoscopy During Transurethral Resection of Bladder Tumor?

Observational Armed Forces Institute of Urology, Rawalpindi · NCT06729346

This study is testing if a special imaging technique can help find hidden bladder tumors that might be missed when doctors look at the bladder during a routine procedure.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorArmed Forces Institute of Urology, Rawalpindi Academic / other
Locations2 sites (Rawalpindi, Punjab Province and 1 other locations)
Trial IDNCT06729346 on ClinicalTrials.gov

What this trial studies

This observational study aims to investigate whether the bladder mucosa that appears normal during white light cystoscopy is truly benign or if it may conceal carcinoma in situ (CIS) or bladder tumors. The study will involve patients undergoing transurethral resection of bladder tumors, focusing on the potential for narrow-band imaging (NBI) to identify hidden tumors that may be missed during standard procedures. By clarifying the reliability of visual assessments during cystoscopy, the study seeks to improve diagnostic accuracy in bladder cancer detection.

Who should consider this trial

Good fit: Ideal candidates for this study are patients aged 18 to 75 who have been diagnosed with a bladder tumor.

Not a fit: Patients outside the age range of 18 to 75 or those without a bladder tumor will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the detection of bladder cancer, leading to earlier and more effective treatment for patients.

How similar studies have performed: While this approach is observational, similar studies have indicated that advanced imaging techniques like NBI can improve tumor detection rates, suggesting potential success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

any patient with bladder tumor

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Exclusion Criteria:

* any patient whose age is less than 18 years any patient whose age is more than 75 years

Where this trial is running

Rawalpindi, Punjab Province and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Transition Cell Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.