Evaluating Tafasitamab with Lenalidomide for Relapsed DLBCL in Italy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The PRO-MIND study is a multicenter, prospective observational cohort study conducted in Italy to assess the effectiveness and safety of tafasitamab in combination with lenalidomide, followed by tafasitamab monotherapy in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) who are not eligible for transplantation. This study collects real-world data on treatment outcomes without mandating specific treatment protocols, allowing physicians to make decisions based on their clinical judgment. Patients will receive tafasitamab and lenalidomide through standard commercial channels, and the study aims to gather insights into the effectiveness of these treatments in a practical setting.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients are aged 18 years or older.
2. Patients with DLBCL R/R disease non-transplant eligible.
3. Patients who will initiate the treatment with commercially available tafasitamab and lenalidomide after the ICF signature. The decision to prescribe tafasitamab must have been made prior and regardless of the enrollment of the patient in the study.
4. Patients are able of giving the signed informed consent.

Exclusion Criteria:

1. Concomitant participation in an interventional clinical study
2. Any patient in the physician's opinion from whom initial diagnosis or follow-up data is unlikely to be obtained reliably data for the purposes of this observational study.
3. Patients who started tafasitamab treatment before signing the ICF.

Where it's running

• Incyte Biosciences Italy S.r.l
  Milan, Italy Recruiting

Study contacts

• Study coordinator: Nicola Battaglia
• Email: NBattaglia@incyte.com
• Phone: + 39 3429513636

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.