Evaluating synovitis in adults with haemophilia A

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the prevalence of synovitis in adult patients diagnosed with haemophilia A. The research focuses on understanding how recurrent joint bleeding, a common complication of this bleeding disorder, leads to inflammation and subsequent joint damage. Utilizing ultrasound technology, the study will document the condition of the synovial tissue and its impact on joint health. Participants will be required to provide detailed medical histories, including bleeding events and treatment regimens, to ensure comprehensive data collection.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Participants (≥ 18 years old) suffering from moderate or severe haemophilia A, also with inhibitor or joint replacement
* Complete documentation of hemophilia severity, treatment history (past 12 months), and bleeding events (past 12 months), inhibitor status (at time of enrollment and in past medical history)
* Submitted written consent to participate in the study

Exclusion Criteria:

* Patients suffering from other bleeding disorders conflicting with the research question
* Patients in clinical studies with investigational drugs

Where it's running

• University Hospital Bonn
  Bonn, North Rhine-Westphalia, Germany Recruiting

Study contacts

• Principal investigator: Andreas C Strauss, PD Dr. med. — University Hospital, Bonn
• Study coordinator: Andreas C. Strauss, PD Dr. med.
• Email: andreas.strauss@ukbonn.de
• Phone: +4922828714176

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  Recruiting Phase 3 Sinocelltech Ltd. · Beijing, Beijing Municipality · NCT07437404

• Different doses of Inno8 for adults with haemophilia A.

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  Recruiting at 25 sites Phase 1 Novo Nordisk A/S · Aurora, Colorado and 32 other locations · NCT07220564

• Targeting abnormal blood flow to treat chronic joint pain in veterans

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  Recruiting Palo Alto Veterans Institute for Research · Palo Alto, California · NCT05700682

• Embolization treatment for patients with hereditary bleeding disorders

  This study is testing whether a new treatment using tiny particles can help people with hereditary bleeding disorders and joint pain feel better and improve their quality of life.

  Recruiting University of Sao Paulo General Hospital · São Paulo · NCT05629130

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.