Evaluating survival factors in patients with Extranodal NK/T-cell Lymphoma
Official title: Prognostic Nomogram of Extranodal NK/T-cell Lymphoma: A Multi-center Retrospective Study
Run by Sun Yat-sen University · NCT04554511 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study looks at what factors might affect how long people with Extranodal NK/T-cell Lymphoma live and how well they respond to treatment, using past patient data to help predict their outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Sun Yat-sen University Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT04554511 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old who have been newly diagnosed with ENKTL during the specified time frame.
✕Probably not a fit
Patients without complete clinical information or those lost to follow-up immediately after treatment may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess prognostic factors affecting overall survival and progression-free survival in patients diagnosed with Extranodal NK/T-cell Lymphoma (ENKTL). It utilizes a retrospective cohort design, analyzing anonymized patient data collected from January 1, 2000, to August 31, 2020. The study will establish a prognostic predictive nomogram to aid in predicting outcomes for ENKTL patients based on their clinical characteristics. Pathological reviews of initial diagnoses will be conducted by designated pathologists to ensure accuracy.
Why it matters
Potential benefit: If successful, this study could provide a valuable tool for predicting patient outcomes and guiding treatment decisions for ENKTL.
How similar studies have gone: Other studies have shown success in using prognostic nomograms for various cancers, suggesting potential for this approach in ENKTL.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients newly diagnosed with ENKTL * Patients diagnosed between January 1, 2000 and August 31, 2020 * Patients older than 18 years Exclusion Criteria: * Patients who did not have complete clinical information or immunohistochemistry, or who were lost follow-up immediately after treatment.
Where it's running
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Sun Yat-sen University Cancer Center
Guangzhou, Guangdong, China Recruiting
Study contacts
- Principal investigator: Hua Wang — Sun Yat-sen University
- Study coordinator: Hua Wang
- Email: wanghua@sysucc.org.cn
- Phone: +862087342462
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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This study follows patients with EBV-positive T/NK-cell disorders to see how they present, what treatments are used, and how they respond over time.
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Frontline immunotherapy versus chemotherapy induction for advanced Extranodal NK/T-cell lymphoma, followed by autologous stem cell transplant
This study tests whether starting with immunotherapy plus targeted drugs is more effective than standard chemotherapy to help patients with advanced extranodal NK/T‑cell lymphoma, then all patients who reach a strict remission proceed to autologous stem cell transplantation.
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Tislelizumab plus Zeprumetostat in relapsed or refractory NK/T-cell lymphoma
This study tests whether combining tislelizumab with zeprumetostat can help patients with relapsed or refractory NK/T-cell lymphoma after prior chemotherapy.
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Treatment for untreated extranodal NK/T-cell lymphoma using a combination of drugs
This study is testing a new combination of drugs to see if it can help people with untreated extranodal NK/T-cell lymphoma feel better and improve their chances of survival.
-
Registry for individuals with T-cell lymphoma
This study is gathering information from people with T-cell lymphoma to help researchers learn more about the disease and improve treatments.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.