Evaluating surgical options for patients with carotid artery stenosis
A Prospective Cohort Study on the Efficacy and Prognosis of Surgical Intervention in Patients With Carotid Artery Stenosis
Xuanwu Hospital, Beijing · NCT06222983
This study is testing two types of surgery for people with narrowed carotid arteries to see which one works better and is safer.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 45 Years to 80 Years |
| Sex | All |
| Sponsor | Xuanwu Hospital, Beijing (other) |
| Locations | 1 site (Beijing) |
| Trial ID | NCT06222983 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the efficacy and safety of surgical interventions, specifically carotid artery stenting (CAS) and carotid endarterectomy (CEA), in patients with carotid artery stenosis. A total of 100 patients aged 45-85 will be enrolled, with a focus on those with significant stenosis. The study will involve preoperative imaging and laboratory examinations to determine the best surgical approach, followed by a series of follow-ups to monitor outcomes such as cognitive function, quality of life, and complications. Additionally, pathological examinations of removed plaques will be conducted to better understand high-risk carotid artery plaques.
Who should consider this trial
Good fit: Ideal candidates are symptomatic patients aged 45-85 with stenosis greater than 50% or asymptomatic patients with stenosis between 70% and 99%.
Not a fit: Patients outside the age range of 45-85 or those with stenosis less than 50% may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical strategies and outcomes for patients with carotid artery stenosis.
How similar studies have performed: Previous studies have shown promising results with similar surgical interventions for carotid artery stenosis, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. The patient is aged 45-85 years old; 2. Symptomatic patients with stenosis degree greater than 50%, or asymptomatic patients with stenosis degree between 70% and 99% (ultrasound, CT or contrast); 3. Can complete regular follow-up; 4. The patient is informed and agrees to participate in the study. Exclusion Criteria: -
Where this trial is running
Beijing
- Xuanwu Hospital, Capital Medical University — Beijing, China (RECRUITING)
Study contacts
- Principal investigator: Lianrui Guo — Xuanwu Hospital, Beijing
- Study coordinator: Lianrui Guo, Dr.
- Email: lianguiguo@sina.com
- Phone: +8613671009746
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Carotid Artery Stenting, Carotid Endarterectomy, Carotid Artery Plaque, Carotid Revascularization