Evaluating storage buffers for gut microbiome samples
Official title: PRObing The Efficacy of Commercial Stage Storage Buffers and Evaluating Gut Metaproteome Variability Between Individuals
Run by University of Vienna · NCT06423508 · Data updated 2026-11-12
This study is testing different storage solutions to see which one best keeps human gut samples fresh over time for research.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 52 (estimated) |
| Sponsor | University of Vienna Academic / other |
| Locations | 1 site (Vienna, State of Vienna) |
| Status | Recruiting |
| Started | December 3, 2024 |
| Main results expected | December 30, 2024 |
| Study ends | September 30, 2025 |
| Registry record updated | March 25, 2025 |
| Trial ID | NCT06423508 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are healthy adults aged 18-70 who are willing to provide informed consent.
✕Probably not a fit
Patients who have taken antibiotics in the past month or have undergone gastrointestinal surgery may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study assesses the effectiveness of various commercial storage buffers for preserving human gut fecal samples over time. It compares these buffers to directly frozen samples using metaproteomic analysis to ensure reliable sample preservation. By collecting fecal samples periodically from volunteers, the study aims to explore inter- and intra-individual variabilities at the proteome level, addressing a critical gap in metaproteomic research. The findings could lead to standardized protocols that enhance reproducibility and comparability in gut microbiome studies.
Why it matters
Potential benefit: If successful, this study could improve the reliability of gut microbiome research, leading to better understanding and treatment of related health conditions.
How similar studies have gone: While the approach of evaluating storage buffers is not widely tested, the importance of sample preservation in metaproteomics is well recognized in the field.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * agreeing to participate after signing the informed consent form and * being 18-70 years old. Exclusion Criteria: * take antibiotics during the previous 1 month * had undergone gastrointestinal surgery
Where it's running
-
UVienna
Vienna, State of Vienna, Austria Recruiting
Study contacts
- Principal investigator: Giacomo Carta, PhD — University of Vienna
- Study coordinator: David Gomez Varela PhD. Senior Scientist, PhD
- Email: david.gomez.varela@univie.ac.at
- Phone: 1427755361
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.