Clinical trial Recruiting at 1 site Observational Ages 18 to 70

Evaluating storage buffers for gut microbiome samples

Official title: PRObing The Efficacy of Commercial Stage Storage Buffers and Evaluating Gut Metaproteome Variability Between Individuals

Run by University of Vienna · NCT06423508 · Data updated 2026-11-12

This study is testing different storage solutions to see which one best keeps human gut samples fresh over time for research.

Quick facts

Study typeObservational
Ages18 Years to 70 Years
SexAll
Enrollment52 (estimated)
SponsorUniversity of Vienna
Academic / other
Locations1 site (Vienna, State of Vienna)
StatusRecruiting
StartedDecember 3, 2024
Main results expectedDecember 30, 2024
Study endsSeptember 30, 2025
Registry record updatedMarch 25, 2025
Trial IDNCT06423508 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are healthy adults aged 18-70 who are willing to provide informed consent.

Probably not a fit

Patients who have taken antibiotics in the past month or have undergone gastrointestinal surgery may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study assesses the effectiveness of various commercial storage buffers for preserving human gut fecal samples over time. It compares these buffers to directly frozen samples using metaproteomic analysis to ensure reliable sample preservation. By collecting fecal samples periodically from volunteers, the study aims to explore inter- and intra-individual variabilities at the proteome level, addressing a critical gap in metaproteomic research. The findings could lead to standardized protocols that enhance reproducibility and comparability in gut microbiome studies.

Why it matters

Potential benefit: If successful, this study could improve the reliability of gut microbiome research, leading to better understanding and treatment of related health conditions.

How similar studies have gone: While the approach of evaluating storage buffers is not widely tested, the importance of sample preservation in metaproteomics is well recognized in the field.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* agreeing to participate after signing the informed consent form and
* being 18-70 years old.

Exclusion Criteria:

* take antibiotics during the previous 1 month
* had undergone gastrointestinal surgery

Where it's running

  • UVienna
    Vienna, State of Vienna, Austria
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.