Evaluating sports activity return after knee surgery in younger patients

FAldini Sport Total Joint Arthroplasty-Knee II: Toward Rehabilitation of Sports Activity Following Total Knee Arthroplasty

NA · Istituto Ortopedico Rizzoli · NCT06383936

This study is testing a special rehab program to help younger patients with knee osteoarthritis safely return to sports after knee surgery.

Quick facts

PhaseNA
Study typeInterventional
Enrollment20 (estimated)
Ages40 Years to 65 Years
SexAll
SponsorIstituto Ortopedico Rizzoli (other)
Locations1 site (Bologna)
Trial IDNCT06383936 on ClinicalTrials.gov

What this trial studies

This study focuses on younger patients aged 40 to 65 who have knee osteoarthritis and wish to return to sports after undergoing non-cemented total knee arthroplasty (TKA). It aims to assess the effectiveness of a specific rehabilitation protocol following the surgery to facilitate a safe return to sports activities. The study recognizes that traditional rehabilitation pathways are often not designed for this active subgroup of patients, who have higher functional demands. By tailoring the approach to their needs, the study hopes to improve postoperative outcomes for these individuals.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 40 to 65 who have been active in sports until knee issues arose.

Not a fit: Patients with rheumatic disorders, extreme knee deformities, or other significant medical conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enable younger patients to safely resume sports activities after knee surgery, improving their quality of life.

How similar studies have performed: While there is limited literature specifically targeting this younger demographic with non-cemented TKA, similar studies have shown promise in improving outcomes for active patients.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* aged between 40 and 65 years,
* both men and women,
* individuals who engaged in sports until knee pathology hindered them. - "Saltin-Grimby Physical Activity Level Scale" 3 or 4.

Exclusion Criteria:

* Patients with rheumatic and/or neuromuscular disorders.
* Patients with extreme knee deformity.
* Patients with secondary osteoarthritis with compromised bone quality.
* Patients with coronal knee instability.
* Pregnant patients.
* Patients with medical conditions or physical conditions incompatible with the use of magnetic resonance imaging and electrostimulation (active and passive implanted biomedical devices, epilepsy, severe venous insufficiency in the lower limbs).

Where this trial is running

Bologna

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Knee Osteoarthritis

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.