Evaluating software predictions of soft tissue changes in orthodontic patients

The Accuracy of Computer Software Prediction of Soft Tissue Profile for Patients Undergoing Fixed Orthodontic Treatment

Al-Azhar University · NCT05978856

This study tests if a computer program can accurately predict changes in the soft tissue of patients getting braces to help improve orthodontic treatment planning.

Quick facts

Study typeObservational
Enrollment30 (estimated)
Ages15 Years to 35 Years
SexAll
SponsorAl-Azhar University (other)
Locations1 site (Assiut, Assuit)
Trial IDNCT05978856 on ClinicalTrials.gov

What this trial studies

This clinical study aims to assess the accuracy of computer software in predicting changes to the soft tissue profile of patients undergoing fixed orthodontic treatment. The study focuses on patients with specific dental classifications and requires comprehensive diagnostic records before and after treatment. By analyzing the software's predictions against actual outcomes, the study seeks to determine its reliability in orthodontic planning and treatment outcomes.

Who should consider this trial

Good fit: Ideal candidates are patients undergoing fixed orthodontic treatment with specific dental classifications and comprehensive diagnostic records.

Not a fit: Patients with missing teeth, craniofacial syndromes, or those who have had prior failed orthodontic treatments may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the precision of orthodontic treatment planning, leading to improved aesthetic outcomes for patients.

How similar studies have performed: While there have been studies on orthodontic software, the specific focus on soft tissue profile prediction in this context may represent a novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
The inclusion criteria included:

* Patient undergo fixed orthodontic treatment with the edgewise technique.
* Skeletal class I.
* Dental class I or II or III.
* Final class I occlusion without spacing or crowding, with normal overjet and overbite (2-4 mm)
* Availability of full diagnostic and therapeutic records before to and following orthodontic treatment, including medical and dental history, dental casts, panoramic and cephalometric x-rays, and photographic photographs.

The exclusion criteria included:

* Missing tooth or significant Bolton discrepancies (more than 3 mm).
* Craniofacial syndromes or skeletal abnormalities.
* Failed orthodontic treatment in the past.
* Cosmetic or reconstructive facial surgery during orthodontic treatment, or up to a year beforehand.
* Using drugs that could reduce the volume of soft tissues.

Where this trial is running

Assiut, Assuit

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Dental Malocclusion, VTO, orthodontic software, prediction

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.