Evaluating SLR Maneuver in Obese Patients with GERD

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the thresholds of the straight leg raise (SLR) maneuver during high-resolution manometry (HRM) in obese patients undergoing preoperative evaluation for bariatric surgery. The study seeks to establish a correlation between the SLR maneuver and esophageal acid exposure, particularly in the context of sleeve gastrectomy, which is known to increase the risk of gastro-esophageal reflux disease (GERD). By analyzing a large cohort of patients, the research intends to identify a precise threshold that could help predict pathological GERD in this population. The findings could lead to improved surgical decision-making and patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Complete and adequate HRM and pH-impedance study performed within 2 weeks
* Successfully performed SLR maneuver (adequate intra-abdominal pressure augmentation)
* Obese with BMI\>35 Kg/m2

Exclusion Criteria:

* Patients under the age of 18
* Patients with prior foregut surgery
* Paraesophageal hiatal hernia
* Scleroderma
* Eosinophilic esophagitis
* Pregnancy

Where it's running

• IRCCS Policlinico San Donato
  San Donato Milanese, Milan, Italy Recruiting

Study contacts

• Study coordinator: Stefano Siboni
• Email: stefano.siboni@grupposandonato.it
• Phone: +393493232750

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.