Evaluating skin flap thickness and glandular tissue in prophylactic mastectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the relationship between skin flap thickness, residual glandular tissue, and the occurrence of skin necrosis in women undergoing prophylactic mastectomy due to hereditary breast cancer risk. It focuses on patients with pathogenic variants in BRCA1/2 and other genes, aiming to optimize surgical techniques to minimize residual tissue while preserving viable skin. The study will involve clinical examinations and imaging to gather data on these factors and their implications for breast cancer risk.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Women that are recommended prophylactic mastectomy at the Department of Plastic Surgery at Umeå University hospital due to hereditary factors that have been investigated by clinical geneticists.
* Age between 18-74 years

Exclusion Criteria:

* Women undergoing mastectomy due to cancer.
* Age \< 18 years or \> 74 years.

Where it's running

• Plastic Surgery Unit, Umeå University hospital
  Umeå, Sweden Recruiting

Study contacts

• Study coordinator: Rebecca Wiberg, MD PhD
• Email: rebecka.wiberg@umu.se
• Phone: +4690-785 0000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.